Tantawy(M),Wang(D),Gbadamosi(M),Yu(F),Zhan... Int J Mol Sci 2026-01-29

...ACAT2 and ACTA1) but did not restore the CFZ-mediated downregulation of sarcomeric genes. Together, these findings defin...

Wang(L),Dai(C),Yang(J),Ma(Y),Ding(X),Fan(X... Int J Biol Sci None

...ACAT2), a key cholesterogenic enzyme, were significantly elevated in melanoma cells. ACAT2-mediated de novo cholesterol ...

Zhang(Y),Shao(Y),Li(X),Zhou(D),Zhou(J),Yan... Commun Biol 2026-02-07

...ACAT2 on lipid accumulation in cervical cancer (CC). ACAT2 expression is enhanced in CC and is closely associated with t...

Bailly(C) Eur J Pharmacol 2026-08-28

...ACAT2). The present review retraces the products history, from their discovery to the characterization of the target eng...

Luo(X),Wang(W),Fang(Y),Tong(M),Qin(B),Cao(... Lipids 2026-08-26

...ACAT2) protein expression were measured. The pathological changes of the liver were observed under a light microscope. C...

Gonzalez(J),Wageman(J),Buchanan(L),Kalayji... Lipids Health Dis 2026-08-24

...ACAT2-mediated cholesterol esterification and in NPC1L1/ABCG5/G8-mediated cholesterol handling. The magnitude of LDL-C r...

Chang(CCY),Fujimoto(T),Yamauchi(Y),Urano(Y... Biomolecules 2026-06-08

...ACAT2) convert free cholesterol into cholesteryl esters for storage, with ACAT1 serving as the predominant isoenzyme in ...

Berger(O),Insler(M),Falah(G),Ben David(G),... Int J Mol Sci 2026-06-08

...ACAT2 (FWER = 0.026). Notably, only the pan-tissue Horvath clock showed a significant genotype effect, with marked age a...

Li(Z),Tsai(HK),Libby(AH),Founds(MW),Murtag... Nat Commun 2026-06-05

...ACAT2 to reveal an unexpected metabolic dependency in cancer cells. A crystal structure of SuPUR ligand-bound ACAT2 reve...

Zhou(Y),Zhu(Y),Zhou(Y),Tong(Z),Zhu(X),Du(X... Appl Biochem Biotechnol 2026-05-00

...ACAT2, GPAT1, and APOB) in MRC-5 cells in vitro. Exosomal LINC01133 decreased the expression of autophagy-related protei...