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ANKRD55 is a key regulator of T cell inflammation in multiple sclerosis.

Wu(C),Jiang(M),Yang(X),Liu(Y),Huang(B),Guo... J Clin Invest 2025-10-15

...CCT3, and CCT6. This facilitates proper microtubule organization and TCR activation. These findings establish ANKRD55 as...

Integrated analysis of gene expression and genomic aberration data in osteosa...

Xiong(Y),Wu(S),Du(Q),Wang(A),Wang(Z) Cancer Gene Ther 2016-08-24

...CCT3, COPS3 and WWP1 were the significant hub proteins. We conclude that these genes, including CCT3, COPS3 and WWP1 are...

Molecular chaperone CCT3 supports proper mitotic progression and cell prolife...

Zhang(Yuanyuan),Wang(Yuqi),Wei(Youheng),Wu... Cancer Lett 2016-07-06

...CCT3 mRNA and protein are highly up-regulated in hepatocellular carcinoma (HCC) tissues, and high level of CCT3 is corre...

Overexpression of chaperonin containing TCP1, subunit 3 predicts poor prognos...

Cui(Xiao),Hu(Zhi-Ping),Li(Zhao),Gao(Peng-J... World J Gastroenterol 2016-03-15

...CCT3 expression was suppressed by small interfering RNA. The effects of reducing CCT3 expression in HCC cells were teste...

Expression and diagnostic value of CCT3 and IQGAP3 in hepatocellular carcinom...

Qian(E-Na),Han(Shuang-Yin),Ding(Song-Ze),L... Cancer Cell Int 2016-07-08

...CCT3 and IQGAP3 levels. Plasma AFP, CCT3 and IQGAP3 protein levels were measured by enzyme linked immunosorbent assay (E...

Modulation of STAT3 folding and function by TRiC/CCT chaperonin.

Kasembeli(Moses),Lau(Wilson Chun Yu),Roh(S... PLoS Biol 2015-06-15

...CCT3. Stat3 binding to TRiC mapped predominantly to the β-strand rich, DNA-binding domain of Stat3. Notably, enhancing S...

MEK1 is associated with carboplatin resistance and is a prognostic biomarker ...

Pénzváltó(Zsófia),Lánczky(András),Lénárt(J... BMC Cancer 2015-07-14

...CCT3, NFAT2CIP, MEK1, FUBP1 and CSDE1. Silencing of MEK1, CSDE1, CNOT8 and RTF1, and pharmacological inhibition of MEK1 ...

Serum antibody response to group II chaperonin from Methanobrevibacter oralis...

Hirai(Kimito),Maeda(Hiroshi),Omori(Kazuhir... Pathog Dis 2014-04-28

...CCT3 and CCT8 in autoimmune disease patients were significantly higher than in controls. Significant differences were al...

Molecular determinants of the ATP hydrolysis asymmetry of the CCT chaperonin ...

Chagoyen(Mónica),Carrascosa(José L),Pazos(... Proteins 2014-11-26

...CCT3, CCT6, CCT8 and CCT1/2/4/5/7. Our results point to a spatial organisation of the CCT subunits in two opposite areas...

Interactions of subunit CCT3 in the yeast chaperonin CCT/TRiC with Q/N-rich p...

Nadler-Holly(Michal),Breker(Michal),Gruber... Proc Natl Acad Sci U S A 2013-02-01

...CCT3) or 6 (CCT6). The mutation in subunit CCT3 was found to induce cytoplasmic foci termed P-bodies where mRNAs, which ...

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