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A novel tumor suppressor CECR2 down regulation links glutamine metabolism contr…

Wang(X),Xu(C),Wang(S),Huang(W),Liu(Y),Zhang(… Clin Transl Oncol 2021-09-00

...CECR2 in tumors was lower than adjacent tissues. Furthermore, deficiency of CECR2 promoted tumor cell growth both in vit...

Cecr2 mutant mice as a model for human cat eye syndrome.

Dicipulo(R),Norton(KA),Fairbridge(NA),Kibaln… Sci Rep 2021-00-04

...Cecr2 is involved in the abnormal features of CES and that Cecr2 mice can be used as a model system to study the wide ra...

The nuclear factor CECR2 promotes somatic cell reprogramming by reorganizing th…

Wu(L),Zhao(G),Xu(S),Kuang(J),Ming(J),Wu(G),W… J Biol Chem 2021-00-00

...Cecr2 expression by directly binding to its promotor region. CECR2 in turn promotes reprogramming by forming a chromatin...

Subfertility in young male mice mutant for chromatin remodeller CECR2.

Norton(KA),Humphreys(R),Weatherill(C),Duong(… Reproduction 2022-00-21

...Cecr2+/+ at P42-60) but improve with age (49% fewer than Cecr2+/+ at P81-100), although never completely recovering to C...

CECR2 drives breast cancer metastasis by promoting NF-κB signaling and macropha…

Zhang(M),Liu(ZZ),Aoshima(K),Cai(WL),Sun(H),X… Sci Transl Med 2022-00-02

...CECR2), was the top up-regulated epigenetic regulator in metastases associated with an increased abundance of M2 macroph...

Mechanistic insights into acetylated histone recognition by the CECR2 bromodoma…

Chakraborty(S),Roy(A),Prusty(S),Sahoo(S),Sud… Biochem J 2026-08-05

Chromatin remodeling regulator CECR2 (cat eye syndrome chromosome region candidate 2) plays critical roles in neurulatio...

Chromatin remodeling factor CECR2 forms tissue-specific complexes with CCAR2 an…

Niri(F),Terpstra(AN),Lim(KRQ),McDermid(HE) Biochem Cell Biol 2021-12-00

...CECR2 is a chromatin remodeling factor that plays an important role in neural tube closure and reproduction. Loss-of-fun...

Cat Eye Syndrome Chromosome Region Candidate 2 (CECR2) in chromatin remodeling …

Ali(M),Rafiq(A),Rakhshan(R),Beigh(MA) Int J Biol Macromol 2025-11-00

CECR2 is a bromodomain-containing epigenetic regulator essential for maintaining chromatin architecture and is implicate...

Mutation analysis of Drosophila dikar/CG32394, homologue of the chromatin-remod…

Keuling(A),Yang(F),Hanna(S),Wang(H),Tully(T)… Genome 2007-08-00

The mammalian CECR2 protein contains a highly conserved bromodomain and forms a chromatin-remodelling complex with the I...

GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Re…

Crawford(TD),Audia(JE),Bellon(S),Burdick(DJ)… ACS Med Chem Lett 2017-07-13

...CECR2). Screening of our internal medicinal chemistry collection led to the identification of a pyrrolopyridone chemical...

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