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Downregulation of Cathepsin B expression alleviates periodontitis by reducing...

Wang(T),Liu(X),Li(J),Ding(Y),Yue(Y),Li(J),... Front Immunol None

...CTSB expression in periodontal tissues. Small-interfering RNA (siRNA) was used to inhibit CTSB expression in macrophages...

A Surface-Enhanced Raman Scattering and Fluorescence Seesaw Nanosensor for th...

Zhu(D),Chen(G),Zhong(H),Lin(D),Wu(Y),Cui(Y... J Phys Chem B 2026-03-26

...CTSB and (2) as linkers bridging the plasmonic Au NPs and TAMRA signal molecules. Upon CTSB-mediated proteolytic cleavag...

Particulate Matter-Induced Lysosomal Rupture-Mediated Pyroptosis in Human Voc...

Choi(H),Bang(J),Song(Y),Kim(CS) J Voice 2026-03-16

...CTSB-specific inhibitor, reduced CTSB expression and suppressed NLRP3, cleaved caspase-1, GSDMD, IL-1β, and CTSB in PM-e...

Cathepsin B promotes asthma potentially via macrophage-associated autophagy a...

Gong(L),Du(J),Wang(J),Zhang(Z),Zhang(J),Xu... J Immunol 2026-03-17

...CTSB-expressing immune cell population, with enrichment of pathways related to apoptosis and autophagy. In vivo, CTSB in...

Exerkine dysregulation links visceral adiposity to skeletal muscle impairment...

Załęska-Kocięcka(M),Mazuruk(M),Szcześniak(... Cardiovasc Diabetol 2026-05-26

...CTSB, DCN, and resistin. In contrast, proteins associated with muscle integrity and regenerative signaling (myostatin, B...

Fucoidan Protects Against Cadmium-Induced Cytotoxicity in PK-15 Cells by Rest...

Qu(H),Zhao(X),Wang(Y),Mao(S),Chen(X),Huang... Toxics 2026-05-13

...CTSB; Cathepsin D, CTSD), and reversed Cd-induced autophagic flux blockade. Importantly, TFEB silencing abolished the pr...

Identification and preliminary clinical validation of type 2 diabetes signatu...

Tang(F),Zuo(X),Wang(W),Sun(R),Cheng(H),Wu(... Front Med (Lausanne) None

...CTSB, NAMPT) were identified as candidate signature genes. ROC analysis showed AUC values of 0.819, 0.931, 0.882, and 0....

Exome analysis of 22,319 individuals links extremely rare copy-number variant...

Quenez(O),Schramm(C),Cassinari(K),Nicolas(... Am J Hum Genet 2026-08-26

...CTSB LoF alleles appear as candidates (OR = 5.03 [1.50; 20.71], p = 0.0089). We then performed exome-wide gene-level dos...

Cathepsin B-Oriented Screening, Isolation, and Antitumor Validation of Bioact...

Hou(W),Zhang(L),Yu(K),Lu(J),Qin(C),Qin(M),... Mar Drugs 2026-07-01

...CTSB-associated enzymatic activity and intracellular CTSB-related fluorescence signals to different extents, with phenol...

Cathepsins are involved in ovarian remodeling post-parturition in black rockf...

Liu(J),Zuo(C),Jing(X),Zhang(X),Niu(C),Liu(... Gen Comp Endocrinol 2026-06-00

...CTSB to the ovarian stromal periphery and specific oocytes. Functional studies using recombinant mature CTSB demonstrate...

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