Ramalingam(Latha),Oh(Eunjin),Thurmond(Debb... Diabetologia 2015-01-29

...Doc2b is naturally limiting for these processes, and whether Doc2b enrichment might exert a beneficial effect upon glyca...

Kabekkodu(Shama Prasada),Bhat(Samatha),Rad... J Biol Chem 2014-06-20

...DOC2B expression. The region -630 to +25 bp of the DOC2B gene showed robust promoter activity by a luciferase reporter a...

Friedrich(Reut),Gottfried(Irit),Ashery(Uri... Front Endocrinol (Lausanne) 2013-09-24

...Doc2B. Interestingly, Munc13-1 co-translocates at a slower rate than Doc2B. Moreover, while Doc2B dislocates from the PM...

Pinheiro(Paulo S),de Wit(Heidi),Walter(Ale... J Neurosci 2013-12-10

...Doc2b, remains enigmatic. We investigated its role in chromaffin cells using Doc2b knock-out mice and high temporal reso...

Giladi(Moshe),Michaeli(Lirin),Almagor(Lior... J Mol Biol 2013-12-27

DOC2B (double-C2 domain) protein is thought to be a high-affinity Ca(2+) sensor for spontaneous and asynchronous neurotr...

Yu(Haijia),Rathore(Shailendra S),Davis(Eri... Mol Biol Cell 2013-10-31

...Doc2b in fusion. These results demonstrate that Doc2b promotes GLUT4 exocytosis by accelerating the SNARE-dependent fusi...

Ramalingam(Latha),Oh(Eunjin),Yoder(Stephan... Diabetes 2012-12-28

...Doc2b heterozygous (Doc2b(+/-)) and homozygous (Doc2b(-/-)) knockout mice exhibited significant whole-body glucose intol...

Pang(Zhiping P),Bacaj(Taulant),Yang(Xiaofe... Neuron 2011-07-01

...Doc2B lacking Ca(2+)-binding sites. Thus, our data suggest that Doc2s are modulators of spontaneous synaptic transmissio...

Friedrich(Reut),Yeheskel(Adva),Ashery(Uri) Mol Neurobiol 2010-06-28

...DOC2B proteins. We created a structural model of DOC2B's C2A based on the crystal structure of rabphilin-3A with and wit...

McMahon(Harvey T),Kozlov(Michael M),Marten... Cell 2010-03-30

...Doc2b deform synaptic membranes during synaptic vesicle exocytosis. We discuss how local curvature generated by these an...