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Germline variants and impact on lung cancer outcomes following chemotherapy: ...

Al-Matrafi(AR),Baxter(MA),Pearson(ER),Pett... Crit Rev Oncol Hematol 2026-06-24

...ERCC1 C118T, and XRCC1 Arg399Gln. For non-platinum-treated NSCLC and SCLC, there was insufficient evidence to conduct a ...

Investigating Genetic Risk to Oxaliplatin-Induced Sinusoidal Obstruction Synd...

Zhang(M),Wang(P),Kong(Y),Gaudio(DD),Parent... Mod Pathol 2026-05-00

...ERCC1, ERCC2, ABCB1, GSTP1, DPYD, MTHFR, ABCC2, UGT1A1, GSTT1, and GSTM1 known to be associated with oxaliplatin toxicit...

Impact of Pharmacogenetic Markers on the Efficacy of Neoadjuvant FLOT Chemoth...

Fedorinov(D),Lyadov(V),Lyadova(M),Abdullae... Int J Mol Sci 2026-05-04

...ERCC1 genotype were observed (p = 0.525). ERCC1 (rs11615) may serve as a potential pharmacogenetic marker of response to...

Phosphorylation by CDK1 switches the function of the human SLX4 SAP domain fr...

Scaglione(S),Gaillard(PH) Nucleic Acids Res 2026-05-05

...ERCC1, MUS81-EME1, and SLX1 structure-specific endonucleases. Interaction with MUS81 relies on the conserved SAP domain ...

Altered lipid profile in mice lacking the DNA repair protein ERCC1.

Dziuban-Lech(D),Lipko(A),Robinson(AR),Czer... DNA Repair (Amst) 2026-05-00

...Ercc1-/- and wild-type (WT) mice. Ercc1-/- MEFs showed significantly reduced FA levels, while in brains and livers, diff...

Biowaste-Archetyped Hierarchical Calcium Carbonate Nanoreactors Induce Tumor ...

Shi(S),Liu(H),Peng(Q),Nan(S),Liu(S),Wei(L)... ACS Appl Mater Interfaces 2026-04-29

...ERCC1)), thereby reversing cisplatin resistance and sensitizing tumor cells to DNA damage. In vivo evaluations in HCC xe...

Nucleotide excision repair and poly(ADP-ribose) polymerase 1 cooperate in HBV...

Hung(HC),Tsai(HW),Li(YT),Liu(WC),Cheng(KH)... JHEP Rep 2026-06-00

...ERCC1, XPF, TDP1, and PARP1 and cccDNA. ERCC1-XPF NER endonuclease and TDP1 increased cccDNA in liver cells and were sho...

A meta-analysis and expression profiling of DNA repair gene polymorphisms in ...

Ye(H),Fang(J),Jin(P) Front Oncol None

...ERCC1 C118T or XPD Asp312Asn across genetic models, whereas ERCC1 8092C>A showed significant associations in homozygous ...

Circular RNA hsa_circ_0003472 Promotes Pancreatic Ductal Adenocarcinoma Progr...

Xia(C),Chen(Y),Yin(X),Zhu(Y),Wang(G),Chen(... Biol Proced Online 2026-04-07

...ERCC1). Rescue experiments confirmed that the oncogenic effects of hsa_circ_0003472 were mediated through the miR-1253/E...

Colchicine Alleviates Non-Atherosclerotic Vascular Aging by Targeting Endothe...

Mohammadi Jouabadi(S),Jüttner(AA),Golshiri... J Inflamm Res None

...ERCC1 knockout (SMC-KO) mouse model of DNA-damage-driven vascular aging. We performed experiments in the SMC-KO treated ...

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