文献库搜索 | GeneLibs

Liu(K),Yang(X),Lin(S),Lin(C),Cai(N),Zeng(L... Biomedicines 2026-06-15

...IAPP expression. This study aimed to investigate the effects of Cav-1 depletion on IAPP secretion and expression and to ...

Kidman(KA),Pedrick(C),Kreck(CA),Mancera(RL... Proteins 2026-06-14

...IAPP and rIAPP. In the case of hIAPP, a general reduction in the likelihood of α-helical conformations was observed, par...

Fu(W),Lu(R),Wang(D),Sang(Z) Bioorg Chem 2026-09-15

...IAPP in T2DM), endoplasmic reticulum stress, and vasculopathy. By systematically examining each pathway, we highlight no...

López Del Castillo(I),Garcia-Martin(J),Gut... Ageing Res Rev 2026-10-00

...IAPP) emerges as a key pathogenic event. In this review, we examine the shift toward an IAPP-centric model of disease, h...

Pfitzer(A),Schulz(CM),Backer(R),Hasecke(F)... Biophys Chem 2026-08-00

...IAPP have been suggested to exhibit cytotoxic activity. Here, we developed an IAPP model, denoted dimIAPP, which assembl...

Valshon(K),Kondrot(K),Uehara(H),Alexander(... Int J Mol Sci 2026-03-26

...IAPP aggregates, ultimately leading to apoptosis. A small but growing body of research also links IAPP-mediated proteoto...

Oh(Y),Palanikumar(L),Howarth(M),Maity(D),A... Biochemistry 2026-04-21

Islet amyloid polypeptide (IAPP) is a 37-residue peptide hormone copackaged and cosecreted with insulin by pancreatic β-...

Bousch(C),Bérubé(F),Babych(M),Ongeri(S),Bo... Int J Mol Sci 2026-03-12

...IAPP derivatives for the treatment of metabolic disorders. Accordingly, elucidating the molecular mechanisms by which IA...

Yoo(YM),Joo(SS) Int J Mol Sci 2026-03-23

...IAPP or amylin) within pancreatic β-cells. IAPP is also a neuropancreatic hormone that plays a significant role in Alzhe...

Panek(S),Van Baelen(AC),Volta(BD),Dutta(SB... J Med Chem 2026-03-26

...IAPP, leading to poor specificity. We report a peptide-guided late-stage diversification strategy to generate BODIPY-bas...