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Chen(S),Li(Y),Nie(X),Zhang(Y),Chen(Q),Xion... CNS Neurosci Ther 2026-02-00

...JAK2/STAT3 activation. Recombinant IL-6 partially restored JAK2/STAT3 signaling and mitigated the growth-inhibitory phen...

Ma(Y),Wang(X),Wei(Z),Zhang(Q),Yuan(F),Xu(C... Cancer Lett 2026-04-28

...JAK2-STAT1-IRF1 downregulation. SLC5A11 knockout abolished these effects, while reconstitution restored metformin respon...

Liu(Z),Xiang(Y),Xie(C),Yin(X),Zhang(M),Che... Thromb Res 2026-03-00

Essential Thrombocythemia (ET) is a myeloproliferative neoplasm driven by JAK2V617F, CALR, and MPL mutations, characteri...

Li(QM),Zhu(ML),Li(X),He(JX),Zha(XQ),Luo(JP... Phytomedicine 2026-04-00

...JAK2) and signal transducer and activator of transcription 5 (STAT5) signaling pathway activation in PD could be allevia...

Yang(Y),Rong(B),Shi(H),Lu(K),Lin(X),Wen(Y)... Eur J Med Chem 2026-04-05

...JAK2 inhibitory activity (JAK2 IC50 = 49 nM). Notably, 4B demonstrated favorable pharmacokinetic properties in mice, ach...

Ma(X),Li(Z),Liu(H),Wang(M),Gao(F),Xiao(Z),... Free Radic Biol Med 2026-04-00

...JAK2 inhibitor fedratinib. Further analysis by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and co-immunopr...

Zheng(J),Rao(YX),Zheng(H),Shi(LL) Cancer Med 2026-02-00

...JAK2/STAT3) signaling pathway. The research findings indicated that FCGBP is significantly overexpressed in glioma and i...

Zhang(W),Jin(C),Liu(S),Wan(X),Li(Y),Liu(J)... Front Immunol None

...JAK2/STAT3-CXCL3 signaling to expand MDSC populations. Concurrently, a hypoxia-lactate-HIF-1α-CD73/A2AR circuit further ...

Li(H),Zhang(S),Feng(C),Cheng(F),Han(Y),Wan... Int J Biol Sci None

...JAK2/STAT3 signaling axis alleviated abnormal osteoblast activation and significantly ameliorated subchondral bone scler...

Huang(M),Yang(F),Song(JC),Wang(X),Jiao(PP)... Biochem Biophys Rep 2026-03-00

...JAK2/STAT3 signaling pathway. A UC model was established by administering 3% DSS in drinking water to male BALB/c mice. ...