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Dysregulated glucose metabolism in the visual cortex of human subjects with m...

Mjaaseth(UN),Hsu(MF),Arballo(J),Haj(FG),Pa... Front Aging Neurosci None

...PTPN1 gene expression. Inflammatory markers including TNF, IL1B, and GFAP were elevated in AD. Sex-stratified analyses r...

System Pharmacology-Based Anti-proliferation and Anti-angiogenesis Mechanisms...

Yang(Y),Tang(SW),Wu(XX),Jiang(WC),Chen(QL) Chin J Integr Med 2026-04-27

...PTPN1-epidermal growth factor receptor (EGFR) interaction pairs regulating the PI3K-Akt signaling pathway. Oridonin was ...

Discovery of Potent and Selective Benzothiophene Difluoromethyl Phosphonate (...

Zheng(XM),Candito(DA),Jewell(J),Childers(M... J Med Chem 2026-05-14

PTPN1 and PTPN2 are interesting targets for immuno-oncology due to their ability to modulate IFNγ signaling and T-cell a...

Negative correlation between microRNA and insulin sensitivity gene expression...

Podraza(J),Wąsowski(M),Jonas(MI),Lisik(W),... Nutr Metab (Lond) 2026-04-13

...PTPN1, PTPN2) is altered in the adipose tissue of patients with obesity due to miRNA interference, predisposing them dir...

Identifying ICAM-1 as a Therapeutic Target for Cytokine Storm in Human Macrop...

Chen(S),Wu(D),Zheng(Z),Luo(Y),Zhang(L) Molecules 2026-03-27

...PTPN1), E74-like ETS transcription factor 4 (ELF4) and guanylate binding protein 2 (GBP2). Then, the LINCS L1000 charact...

PTPN1/PTPN2 inhibition improves NK cancer therapy by enhancing IL-2 and mitig...

Feng(CH),Peltier(L),Chouleur(T),DiPonzio(M... EMBO Rep 2026-05-00

...PTPN1 and PTPN2 (PTPN1/N2) in NK cells significantly enhances anti-tumor cytolytic activity both in vitro and in vivo. T...

Integrating Untargeted Metabolomics and Transcriptomics in Mice with Pulmonar...

Sha(Y),Zhao(X),Zhu(H),Li(Y),Shao(M),Ding(S... Pathogens 2026-02-27

...Ptpn1, Dgat2, and Alox5ap and downregulated Cyld, Zfp61, and Mapk11. Metabolomic profiling revealed 113 differentially a...

PTP1B Inhibitors for Type 2 Diabetes: From Natural Products, Synthetic Inhibi...

Joshi(P),Mazumder(A),Pentela(B),Debnath(A) Curr Drug Targets 2026-03-30

...PTPN1", combined with inhibitor, drug discovery, type 2 diabetes, insulin resistance, and structural biology terms. Natu...

Machine learning and free energy clustering reveal PAH protein binding linked...

Chen(C),He(Y),Ni(Y),Song(D),Chu(M),Zhang(W... iScience 2026-04-17

...PTPN1, and ITGA4 as candidate core PAH targets enriched in neuroinflammation, microglial activation, lipid metabolism, a...

Network pharmacology refined with non-ubiquity and decoy-controlled molecular...

Santos-Enriquez(AK),Dayrit(FM),de Jesus(AJ... Front Bioinform None

...PTPN1), 11-beta-hydroxysteroid dehydrogenase 1 (HSD11B1), peroxisome proliferator-activated receptor α (PPARα), peroxiso...

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