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Molecular insights into the association of obesity with breast cancer risk: r...

Naushad(Shaik Mohammad),Hussain(Tajamul),A... Mol Cell Biochem 2015-02-24

...RalGDS/AF-6) domain family member 1 (RASSF1A) (r = 0.31, p < 0.001), and breast cancer type 1 susceptibility protein (r ...

Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent...

Mazhab-Jafari(Mohammad T),Marshall(Christo... Proc Natl Acad Sci U S A 2015-08-28

...RALGDS) proteins. Gain-of-function KRAS mutations occur frequently in human cancers and predict poor clinical outcome, w...

Preoperative serum methylation signature as prognostic tool after curative he...

Kanekiyo(Shinsuke),Iizuka(Norio),Tsunedomi... Anticancer Res 2015-04-09

...RalGDS/AF-6) domain family member 1, serine peptidase inhibitor Kunitz type 2, cystic fibrosis transmembrane conductance...

Detection of recurrent alternative splicing switches in tumor samples reveals...

Sebestyén(Endre),Zawisza(Michał),Eyras(Edu... Nucleic Acids Res 2015-06-18

...RALGDS, MITF, PRDM1, ABI1 and MYH11, for which the switch implies a change in the protein product. Moreover, some of the...

DNA methylation-based prognosis and epidrivers in hepatocellular carcinoma.

Villanueva(Augusto),Portela(Anna),Sayols(S... Hepatology 2015-08-04

...RalGDS/AF-6] domain family member 1, insulin-like growth factor 2, and adenomatous polyposis coli) and other solid tumor...

RalA signaling pathway as a therapeutic target in hepatocellular carcinoma (H...

Ezzeldin(Mohamad),Borrego-Diaz(Emma),Taha(... Mol Oncol 2015-02-21

...RalGDS were also expressed at higher levels in malignant samples. Inhibition of RalA by gene-specific silencing caused a...

Conserved electrostatic fields at the Ras-effector interface measured through...

Walker(David M),Wang(Ruifei),Webb(Lauren J... Phys Chem Chem Phys 2015-10-16

...RalGDS) to make comparisons between the docked complexes formed when either of the two effectors bind to WT Ras. This co...

RASSF5 inhibits growth and invasion and induces apoptosis in osteosarcoma cel...

Zhou(Xu-Hui),Yang(Chao-Qun),Zhang(Cheng-Li... Oncol Rep 2015-06-01

...RalGDS/AF-6) domain family member RASSF5 has been implicated in a variety of key biological processes, including cell pr...

Repression of CD24 surface protein expression by oncogenic Ras is relieved by...

Pallegar(Nikitha K),Ayre(D Craig),Christia... Front Cell Dev Biol 2015-08-24

...RalGDS pathway only partially affected protein expression. Surprisingly, inhibition of MEK with U0126 only partially res...

Construction of chimeric E3s expression plasmids targeting oncoprotein ras.

Ma(Yi-hui),Zhang(Qiang),Gu(Yu-mei),Lu(Chao... Zhongguo Yi Xue Ke Xue Yuan... 2014-01-09

...RalGDS, and the function domain of F-Box as well as the U-Box to construct the plasmids. Then used the double enzyme, PC...

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