Wu(Z),Li(J),Hu(J),Lai(C),Li(Z),Yu(H),Yuan(... Discov Oncol 2026-02-27

...RALGDS, which were incorporated into an M2-related gene signature (M2GS). ROC analysis affirmed the model’s predictive c...

Demirbas(E),Jang(H),Kosoglu(K),Nussinov(R)... Biophys J 2026-02-17

...RalGDS/Ral pathway plays a more significant role in the progression of Ras-driven colon and pancreatic cancers than the ...

Simanshu(DK),McCormick(F) Biochem J 2026-05-06

...RalGDS, and other downstream effectors. Quantitative binding data, supported by structural insights into effector recogn...

Song(J),Li(N),Dong(X),Xie(J),Lai(H),Zhu(H)... Curr Issues Mol Biol 2025-07-18

This study investigated the isoforms of porcine-origin Ral guanine nucleotide dissociation stimulator (RalGDS) in LLC-PK...

Muratcioglu(Serena),Chavan(Tanmay S),Freed... Structure 2016-04-13

...RalGDS, and additional effectors. This interface has to be inhibitory to such effectors. The second, helical interface a...

Rodriguez(Roberto A),Yu(Lili),Chen(Liao Y) J Chem Theory Comput 2016-06-20

...RalGDS complex, choosing three centers on RalGDS and three on Ras (m = n = 3). At a computing cost of about 71.6 wall-cl...

Dunne(Philip D),Dasgupta(Sonali),Blayney(J... Clin Cancer Res 2016-10-13

...RalGDS-RalA pathways. Moreover, EphA2 levels were elevated in several invasive daughter cell lines, and downregulation o...

Sehgal(Manika),Gupta(Rajinder),Moussa(Ahme... PLoS One 2016-05-03

...ralgds and akt3 via our novel designed parameters illustrating high statistical significance. These novel parameters can...

Wang(Z),Zhou(Y),Hu(X),Chen(W),Lin(X),Sun(L... Cell Death Dis 2016-06-21

...RalGDS. Immunofluorescence microscopy revealed that RalGDS can be recruited to the late endosomal compartments by RILP. ...

Huang(Chun),Wang(Wei-Min),Gong(Jian-Ping),... Asian Pac J Cancer Prev 2015-01-10

...RalGDS pathways. In the clinical field, K-ras oncogene activation is frequently found in human cancers and thus may serv...