Wang(W),Huang(Y),Guo(X),Cao(Z),Jiang(H),Zh... Cell Signal 2026-08-00

...ROCK2/NF-κB signaling as a potential key pathway. LCZ696 suppressed PA- and HFD-induced activation of ROCK2, as evidence...

Chen(X),Chen(J),Chen(Z),Lian(D),Wang(J),Wu... Front Pharmacol None

...ROCK2 signaling axis. We integrated a retrospective cohort analysis with mechanistic validation. Clinically, 85 elderly ...

Chen(Y),Li(B),Lin(Y),Sha(W),Shi(C),Wang(M)... Circ Res 2026-04-24

...ROCK2/MLC (myosin light chain) signaling to inhibit platelet activation. A high-fiber diet upregulated acetate/Olfr78 si...

Gaugel(J),Haacke(N),Kuropka(B),Jähnert(M),... Mol Metab 2026-05-00

...Rock2) and cell adhesion (integrin receptors). In line with this, Picalm knockdown resulted in impaired maturation and l...

Ren(X),Zhang(X),Wang(W),Zhang(M),Bi(X),Pen... J Alzheimers Dis 2026-04-00

...ROCK2 were further investigated. ELISA validation conducted on another 8 VCI patients and 8 HCs showed levels of CAP1 (2...

Yang(R),Zhang(J),Feng(X),Huang(R),Wang(W),... Biochem Pharmacol 2026-07-00

...Rock2. Furthermore, GN11 reduces the expression of the lncRNA Oip5-os1, thereby diminishing its antagonistic effect on m...

Holden(P),Sun(YY),Zientek(K),Wilmarth(PA),... Sci Rep 2026-03-18

...ROCK2, MSN, TPM2, VIM, NF2), protein degradation (USP9X, LAMP1, SYNV1, UBE2L3), and nuclear proteins (LMNA, DFFA, CHMP3,...

Liu(W),Ju(J) J Med Chem 2026-03-12

...ROCK2 inhibitor, whose design was guided by the identification of a novel hydrophobic surface unique to ROCK2. The compo...

Pătru(IR),Atasiei(DI),Ionescu(RT),Negru(AG... Int J Mol Sci 2026-05-14

...ROCK2, HLA-linked susceptibility signals, and T-cell receptor clonality markers. The AI-assisted clustering broadly reca...

Zhang(T),Feng(H),Li(L),Wang(S),Wu(L),Yan(C... J Ethnopharmacol 2026-10-28

...ROCK2-Cofilin signaling pathway. Primary hippocampal cells were transfected with lentivirus to inhibit TRPC6 expression,...