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A metabolic shift favoring sphingosine 1-phosphate at the expense of ceramide...

Abuhusain(Hazem J),Matin(Azadeh),Qiao(Qiao... J Biol Chem 2014-02-21

...SGPP2) expression. Inhibition of S1P production by cultured glioblastoma cells, using a highly potent and selective SPHK...

Vitamin D-responsive SGPP2 variants associated with lung cell expression and ...

Reardon(Brian J),Hansen(Joyanna G),Crystal... BMC Med Genet 2014-01-06

...SGPP2. In Health ABC, SGPP2 SNPs were associated with FEV1 in both European- and African-Americans, and the gene-level a...

Annexin A1 interaction with the FPR2/ALX receptor: identification of distinct...

Bena(Stefania),Brancaleone(Vincenzo),Wang(... J Biol Chem 2012-09-26

...SGPP2. By comparison, serum amyloid A non-genomic responses were reliant on extracellular loops I and II, whereas the sm...

Use of germline polymorphisms in predicting concurrent chemoradiotherapy resp...

Chen(Pei-Chun),Chen(Yen-Ching),Lai(Liang-C... Int J Radiat Oncol Biol Phy... 2012-05-11

...SGPP2 and FARSB on chromosome 2q36.1, was significantly associated with a 3.93-fold increase in pathologic complete resp...

Sphingosine pathway deregulation in endometriotic tissues.

Santulli(Pietro),Marcellin(Louis),Noël(Jea... Fertil Steril 2012-05-30

...SGPP2 expression was decreased in eutopic and ectopic endometrium of endometriosis-affected women (1.7- and 16.7-fold, r...

Downstream gene activation of the receptor ALX by the agonist annexin A1.

Renshaw(Derek),Montero-Melendez(Trinidad),... PLoS One 2011-02-18

...SGPP2), involved in regulation of the sphingosine 1 phosphate chemotactic system. Up-regulation of this gene, as well as...

Sphingosine-1-phosphate Phosphatase 2 Regulates Pancreatic Islet β-Cell Endop...

Taguchi(Yoshimitsu),Allende(Maria L),Mizuk... J Biol Chem 0000-00-00

...Sgpp2 gene deleted. In contrast to Sgpp1(-/-) mice, Sgpp2(-/-) mice had normal skin and were viable into adulthood. Unex...

Sphingosine-1-phosphate phosphatase 2 promotes disruption of mucosal integrit...

Huang(Wei-Ching),Liang(Jie),Nagahashi(Masa... FASEB J 0000-00-00

...Sgpp2-null mice failed to mount a DSS-induced systemic inflammatory response. Of interest, Sgpp2 deficiency suppressed D...

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