...SOCS3 silencing in tumour cells inverts the IL-6-IDO relationship seen in dendritic cells, generating an autocrine IDO-K...
...SOCS3 in immune cells. Functional assays confirmed SQLE promoted while SOCS3 inhibited adipogenesis. Modulating these ge...
...Socs3) showed minimal changes across stages, receptor subunits (Il10ra, Il10rb) and IL-10-responsive effectors (such as ...
...Socs3) compared with WT cells. Importantly, Nlrc5-/-macrophages showed enhanced efferocytosis and reduced antigen presen...
...SOCS3 stratification (SOCS3-High: n = 4; SOCS3-Low: n = 15). Differential gene analysis, pathway enrichment, and CellCha...
...Socs3 was highly expressed in naive embryonic stem cells (ESCs) but minimally detected in EpiSCs. Socs3 deletion uncoupl...
...SOCS3, CXCL1, ICAM1, IL6, PTGS2, CCL2). LS showed increased activated mast cells, eosinophils, neutrophils, and monocyte...
...SOCS3 and TNFα expression and increased POMC expression. Furthermore, chronic ICV administration of β-HB from the onset ...
...SOCS3 and STAT3 by directly binding to both proteins. This interference alleviates SOCS3-mediated suppression of JAK act...
...SOCS3, FKBP5, and HBB. Notably, SST expression was significantly reduced, whereas the other four genes showed marked upr...
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