Literature Search

Li(Z),He(Y),Shen(Y),He(M),Lin(T),Yang(J),Mu(… Insect Biochem Mol Biol 2026-04-00

...Syk/PLCγ2/Akt signaling cascade to block thrombus initiation, while simultaneously inhibiting the ADP receptor P2Y12, di...

Górniak(P),Polak(A),Rams(A),Kupcova(K),Głodk… Cell Death Dis 2026-02-11

...SYK and PI3Kδ inhibitors. Since phenothiazines have well-defined safety and pharmacokinetic profiles, our data provide a...

Rajasheker(KV),Pallavi(MS),Singh(P),Stupin(V… Sci Rep 2026-02-11

Spleen tyrosine kinase (SYK) plays a pivotal role in immunoreceptor signalling pathways implicated in various cancers an...

Zhang(F),Fu(R),Lin(Z),Hu(Q),Zheng(D),Zhang(H… Cardiovasc Res 2026-08-26

...Syk and siFos were performed in RAECs. Western diet feeding of ApoE-/- mice resulted in elevated KMT2B expression and H3...

Bao(A),Gong(X),Lin(S),Gao(C),Wang(H),Wang(D)… J Med Chem 2026-02-12

...Syk and PLCγ2 phosphorylation and subsequent platelet activation. In contrast, compound 31 exerts its antiplatelet effec...

Yan(C),Kong(Z),Pan(Y),Fu(Z),Han(K),Zhao(X),Z… J Control Release 2026-04-10

...SYK) signaling pathway through the local secretion of anti-CLEC7A nanobody. In the APP/PS1 mouse model of AD, these in s...

Shi(L),Zhao(L),Li(X),Chen(X),Wang(K) J Orthop Res 2026-02-00

...Syk) signaling pathway. These findings provide a critical theoretical foundation for further research and development of...

Cho(S),Szalai(TV),El Gaamouch(F),Bajusz(D),K… ACS Med Chem Lett 2026-02-12

...SYK phosphorylation in TREM2-expressing cells, and promoted microglial phagocytosis. Together, these findings establish ...

Ugbaja(SC),Nkabinde(SA),Nkabinde(M),Gqaleni(… Biomedicines 2026-04-30

...SYK pathways. These results necessitate further experimental and clinical validation, providing a solid computational ba...

Chen(Z),Zhang(Y),Chen(S),Zhang(C),Gu(R),Wang… Pharmaceuticals (Basel) 2026-04-30

...SYK as a key target enriched in the NF-κB signaling and osteoclast differentiation pathways. Experimental validation con...