Dennis(Michael D),Coleman(Catherine S),Berg(… Sci Signal 2015-03-30

...TBC1D7 (Tre2-Bub2-Cdc16 domain family member 7)], thereby stimulating the mTORC1 activator Rheb (Ras homolog enriched in...

Capo-Chichi(José-Mario),Tcherkezian(Joseph),… J Med Genet 2014-07-14

...TBC1D7, in the regions of homozygosity shared by the affected siblings. We show that this mutation abolishes TBC1D7 expr...

Menon(Suchithra),Dibble(Christian C),Talbott… Cell 2014-04-23

...TBC1D7 complex (the TSC complex) to turn on Rheb, an essential activator of mTORC1. However, the mechanistic basis of ho...

Anttila(Verneri),Winsvold(Bendik S),Gormley(… Nat Genet 2013-10-17

...TBC1D7, FUT9, STAT6 and ATP5B.

Dibble(Christian C),Elis(Winfried),Menon(Suc… Mol Cell 2013-01-30

...TBC1D7 is unlikely to represent TSC3. TBC1D7 knockdown decreases the association of TSC1 and TSC2 leading to decreased R...

Sato(Nagato),Koinuma(Junkichi),Ito(Tomoo),Ts… Genes Chromosomes Cancer 2010-05-19

...TBC1D7 protein, whereas knockdown of TSC1 expression decreased the level of TBC1D7 protein, suggesting that TBC1D7 is st...

Yoshimura(Shin-Ichiro),Egerer(Johannes),Fuch… J Cell Biol 2007-12-12

...TBC1D7, and EVI5like, are involved in primary cilia formation. However, other human Rabs and GAPs are not. Additionally,...

Gai(Zhongchao),Chu(Wendan),Deng(Wei),Li(Wenq… J Mol Cell Biol 0000-00-00

...TBC1D7 through its direct interaction with the TSC1 coiled coil (CC) region. Loss of TBC1D7 is associated with intellect...

Wang(Y),Hong(X),Wang(J),Yin(Y),Zhang(Y),Zhou… Oncogene 0000-00-00

...TBC1D7 protein complex and mTORC1-independent manner, contributing to intrinsic resistance to rapamycin. Rheb-Y35N trans...

Gorbunova(Elena E),Simons(Matthew J),Gavrilo… MBio 0000-00-00

...TBC1D7, and endogenous TSC2 reciprocally coprecipitated N protein from ANDV-infected MECs. TSCs normally restrict RhoA-i...