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Protective effect of nicotinamide mononucleotide against soybean isoflavone ind…

Wang(K),He(H),Jin(Y),Zhang(F),Ma(R),Wang(F),… Reprod Biol 2025-12-00

...Vav2 gene in the cAMP signaling pathway in mouse testes. In contrast, treatment with 100 mg/kg NMN significantly allevia...

The Cytoskeleton in Adrenal Physiology and Tumours: Functional Roles and Emergi…

Catalano(R),Nozza(E),Esposito(E),Di Bari(S),… Int J Mol Sci 2025-10-24

...VAV2 are involved in signal transduction, cell cycle regulation, and cytoskeletal remodelling. In ACC, dysregulation of ...

VAV2 Drives EGFR-Mediated Rac1 Responses in Prostate Cancer.

Baker(MJ),Zhang(S),Zhang(D),Searle(J),Lal(P)… Mol Cancer Res 2025-08-04

...VAV2 as the foremost mediator EGF-induced GTP loading onto Rac1 in prostate cancer cells. Depletion of VAV2 from prostat...

The tyrosine kinase inhibitor LPM4870108 impairs learning and memory and induce…

Duan(S),Li(C),Gao(Y),Meng(P),Ji(S),Xu(Y),Mao… Arch Toxicol 2022-00-00

...Vav2, and Satb2) known to regulate learning and memory. Increased mRNA and protein expression levels of hippocampal Dnmt...

Targeting CCL2-CCR4 axis suppress cell migration of head and neck squamous cell…

Ling(Z),Li(W),Hu(J),Li(Y),Deng(M),Zhang(S),R… Cell Death Dis 2022-00-17

...Vav2)- Rac family small GTPase 1 (Rac1) complex to activate the phosphorylation of myosin light chain (MLC), which is in...

Hedgehog signaling is controlled by Rac1 activity.

Tang(C),Wu(X),Ren(Q),Yao(M),Xu(S),Yan(Z) Theranostics 2022-00-00

...Vav2, resulting in the increased phosphorylation levels of Vav2 at Y172, which further activates Rac1. The role of Rac1 ...

Differential expression and analysis of extrachromosomal circular DNAs as serum…

Xu(G),Shi(W),Ling(L),Li(C),Shao(F),Chen(J),W… J Clin Lab Anal 2022-06-00

...VAV2, CircD-GATAD2A, CircD-CAB39L, CircD-KHDC1, CircD-FOXN3, CircD-SULT2B1, CircD-DPP9, and CircD-CSNK1D. qPCR demonstra...

A genome-wide association study on frequent exacerbation of asthma depending on…

Son(JH),Park(JS),Lee(JU),Kim(MK),Min(SA),Par… Respir Med 2022-00-00

...VAV2, CCDC150, CCDC30, CATSPER3, ARMH2, and MPRIP (permutated P = 9.23 × 10-5 - 5.50 × 10-4)-were associated with asthma...

Vav2 is a novel APP-interacting protein that regulates APP protein level.

Zhang(Y),Yang(X),Liu(Y),Ge(L),Wang(J),Sun(X)… Sci Rep 2022-00-26

...Vav2, a guanine nucleotide exchange factor (GEF) for Rho family GTPase, is a novel interaction partner of APP. We found ...

The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal …

Lorenzo-Martín(LF),Menacho-Márquez(M),Fernán… Oncogene 2022-00-00

...Vav2 and Vav3 regulate the number, functional status, and responsiveness of hair follicle bulge stem cells. This is link...

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