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Identification of Mannose-Capped-Arabinomannan 101-mer as a Potential Influenza…

Zhang(YF),Xu(R),Luo(J),Ma(Y),Xiao(G),Liu(Y) Adv Sci (Weinh) 2026-04-00

...Syk/NF-κB signaling. This study provided a new oligosaccharide candidate that can satisfy the required "efficacy-safety"...

Paeoniflorin Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disea…

Liu(Y),Tao(J),Tan(D),Zheng(F),Su(Z),Yuan(J),… Research (Wash D C) None

...SYK/SH3BP2 signaling pathway as the crucial mechanism driving MASLD pathogenesis. PF effectively attenuated hepatic meta...

Syk activation during FcγR-mediated phagocytosis involves Syk palmitoylation an…

Jansen(M),Strub(JM),Chaloin(L),Coopman(P),Be… Life Sci Alliance 2026-04-00

...Syk-Cys by the DHHC5 enzyme that specifically associates with Syk upon phagocytosis. Syk palmitoylation is important for...

Porphyromonas gingivalis-derived extracellular vesicles aggravate bone destruct…

Guo(J),Qiu(Q),Yan(X),Zhang(Z),Zhang(X),An(N)… Int J Oral Sci 2026-02-05

...Syk). In vivo, Pg EVs exacerbated RA-induced bone destruction by activating Syk-dependent osteoclastogenesis. R406, a Sy...

Small Molecule Agonists of TREM2 Reprogram Microglia and Protect Synapses in Hu…

Nada(H),Yuan(S),Gaamouch(FE),Cho(S),Gabr(MT) bioRxiv 2026-01-21

...Syk phosphorylation, activated downstream NFAT transcriptional signaling, enhanced APOE internalization and microglial p...

Acetyl tributyl citrate as a new risk factor for osteoporosis: An integrated st…

Qin(S),Li(L),Tang(G),Mu(Y),Deng(Z) Ecotoxicol Environ Saf 2026-01-15

...SYK, BRD4, PTK2B, ADAMTS5), which demonstrated strong binding affinity with ATBC in molecular docking and exhibited stab...

Immune thrombocytopenia in patients with connective tissue disease.

Liu(K),Zheng(Z),Chen(S),Liu(Y),Zhang(G),He(T) Clin Rheumatol 2026-03-00

...Syk) and Bruton's tyrosine kinase (BTK) inhibitors, as well as neonatal Fc receptor (FcRn) inhibitors, have shown consid...

METTL3 promotes neutrophil extracellular trap formation via SYK/ERK/MEK signali…

Luo(S),Zhang(Q),Zhou(W),Zhang(L),Liao(C),Zen… J Adv Res 2026-01-22

...SYK phosphorylation and downstream ERK/MEK activation. Mechanistically, METTL3 promotes m6A methylation of SYK mRNA, enh...

TREM-1 Blockade Inhibits Inflammasome Activation and Pyroptosis: Novel Insights…

Molad(Y),Lagovsky(I),Kliminski(V) Immunology 2026-06-00

...Syk, indicating that inhibition of TREM-1 modulates the activation state of Syk. Both LP17 and iSyk reduced the level of...

Efficient Discovery of Syk-Targeting Phenolic Acids from Orthosiphon aristatus …

Qin(G),Sha(W),Zhang(M),Li(B),Guo(P),Wang(C),… J Agric Food Chem 2026-01-14

...Syk and then inhibit the GPVI pathway, which is unique to collagen-induced aggregation. The work laid the foundation for...

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