...Syk/NF-κB signaling. This study provided a new oligosaccharide candidate that can satisfy the required "efficacy-safety"...
...SYK/SH3BP2 signaling pathway as the crucial mechanism driving MASLD pathogenesis. PF effectively attenuated hepatic meta...
...Syk-Cys by the DHHC5 enzyme that specifically associates with Syk upon phagocytosis. Syk palmitoylation is important for...
...Syk). In vivo, Pg EVs exacerbated RA-induced bone destruction by activating Syk-dependent osteoclastogenesis. R406, a Sy...
...Syk phosphorylation, activated downstream NFAT transcriptional signaling, enhanced APOE internalization and microglial p...
...SYK, BRD4, PTK2B, ADAMTS5), which demonstrated strong binding affinity with ATBC in molecular docking and exhibited stab...
...Syk) and Bruton's tyrosine kinase (BTK) inhibitors, as well as neonatal Fc receptor (FcRn) inhibitors, have shown consid...
...SYK phosphorylation and downstream ERK/MEK activation. Mechanistically, METTL3 promotes m6A methylation of SYK mRNA, enh...
...Syk, indicating that inhibition of TREM-1 modulates the activation state of Syk. Both LP17 and iSyk reduced the level of...
...Syk and then inhibit the GPVI pathway, which is unique to collagen-induced aggregation. The work laid the foundation for...
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