Literature Search

Angliker(Nico),Burri(Michael),Zaichuk(Marian… Eur J Neurosci 2016-08-03

...TSC1 revealed a striking overlap in Purkinje cell degeneration and death, which included neurofilamentopathy and reactiv...

Wu(Huijuan),Chen(Jianchun),Xu(Jinxian),Dong(… J Am Soc Nephrol 2016-08-11

...Tsc1 and rpS6 double-mutant mice. Furthermore, pharmacologic treatment of Tsc1 single-mutant mice with rapamycin reduced...

Hu(Zhongdong),Wang(Ying),Huang(Fuqiang),Chen… J Biol Chem 2016-02-16

...Tsc1 knock-out mice were abolished by mTOR inhibitor rapamycin. Furthermore, BEX2 was also increased in the liver of a h...

Sundberg(Maria),Sahin(Mustafa) J Child Neurol 2016-08-15

...Tsc1 and Tsc2 that link cerebellar circuitry to the development of autistic-like features. Taken together, these preclin...

Komatsu(N),Fujita(Y),Matsuda(M),Aoki(K) Oncogene 2016-02-17

...TSC1, TSC2 and Deptor, which occurred more significantly in BRaf-mutant cells than in KRas-mutant cells. These findings ...

Ito(Yoshitaka),Kawano(Haruna),Kanai(Fumio),N… Int J Oncol 2016-02-04

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder caused by TSC1 or TSC2 mutations. TSC causes the deve...

Huynh(Hung),Hao(Huai-Xiang),Chan(Stephen L),… Mol Cancer Ther 2016-02-01

...TSC1 and TSC2, functions as a negative regulator of mTOR signaling. In the current study, we discovered that TSC2 loss-o...

Xu(Yanhui),Li(Ziru),Yin(Yue),Lan(He),Wang(Ju… PLoS One 2016-01-13

...TSC1) loxp/loxp mice increased the differentiation of Th17 cells in spleen, which was associated with an increment in th...

Fang(Fang),Sun(Shaogang),Wang(Li),Guan(Jun-L… J Bone Miner Res 2016-03-25

...Tsc1 and the sequelae of Tsc1 dysfunction in bone are unknown. In this study, we generated a mouse model of TSC with a d...

Kenerson(Heidi L),Subramanian(Savitha),McInt… PLoS One 2016-01-19

...Tsc1-/-;S6k1-/- mice had lower body weights but higher liver TG levels compared to that of the Tsc1-/- mice. However, th...