...TSC2. Two lines were established (TPK1 and TPK3) each with approximately 30 copies of the transgene. Both lines produced...
...Tsc2) are responsible for Eker renal carcinomas (RC). In humans, alteration in the TSC2 gene is known to cause the tuber...
...TSC2). Loss of heterozygosity (LOH) for TSC2 was further demonstrated in the renal angiomyolipoma. Coupled with the resu...
...TSC2 tumor suppressor gene. The TSC1 gene on chromosome 9q34 encodes a 130 kDa protein named hamartin, and the TSC2 gene...
...TSC2). The aim of the study is to adopt a diagnosis of the disease on DNA level.,111 DNA samples were collected from 45 ...
...TSC2/Tsc2, in a head-to-head orientation. To clarify the regulation of these divergent genes, we studied the promoter ac...
...TSC2). These genes act as tumor suppressor genes, but the mechanism of hamartomatous growth is not completely understood...
...Tsc2 gene mutant (Eker) rats. One gene, selected for further investigation, was named "Niban" "second" in Japanese), bec...
...TSC2, the genes responsible for the disorder, through to gaining insights into the functions of their protein products h...
...TSC2 gene product, tuberin, was seen in three cases. One case studied cytogenetically disclosed a t(3;10). Follow-up dat...
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