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TP53 BRCA1 CRISPR single-cell cancer

Ong(A C),Harris(P C),Davies(D R),Pritchard(L… Kidney Int 1999-12-02

...TSC2 and PKD1, using monoclonal antibodies (mAbs) to both extreme N-(7e12) and C-terminal (PKS-A) regions of the protein...

Arai(Y),Edwards(V),Becker(L E) Acta Neuropathol 1999-11-05

...TSC2 gene product, tuberin, and vimentin, but similar cells in tuber tissue showed consistent immunoreactivity. Balloon ...

Fukuda(T),Kobayashi(T),Yasui(H),Tsutsumi(M),… Virchows Arch 1999-06-03

Alterations in the rat tuberous sclerosis gene (Tsc2) are responsible for the hereditary renal carcinomas (RCs) of Eker ...

Verhoef(S),Bakker(L),Tempelaars(A M),Hesseli… Am J Hum Genet 1999-06-24

...TSC2. In five families, somatic mosaicism was present in a mildly affected parent of an index patient. In one family wit...

Toyoshima(M),Ohno(K),Katsumoto(T),Maki(H),Ta… Brain Dev 1999-07-23

...TSC2, act as tumor suppressors, but the mechanism of hamartomatous growth in several tissues is not completely understoo...

Wang(Q),Verhoef(S),Tempelaars(A M),Bakker(P … Hum Mutat 1999-04-19

...TSC2), of which the TSC2 gene has been cloned. To date, only 35 mutations in the TSC2 gene have been described ranging f...

van Slegtenhorst(M),Verhoef(S),Tempelaars(A)… J Med Genet 1999-06-10

...TSC2 gene. The disease is characterised by a broad phenotypic spectrum that can include seizures, mental retardation, re...

Ito(N),Rubin(G M) Cell 1999-03-18

...TSC2, a gene mutated in half of TSC patients. Clones of gigas mutant cells induced in imaginal discs differentiate norma...

Jones(A C),Shyamsundar(M M),Thomas(M W),Mayn… Am J Hum Genet 1999-05-20

...TSC2 loci in clinically ascertained TSC and support a difference in severity of TSC1- and TSC2-associated disease.

Kobayashi(T),Minowa(O),Kuno(J),Mitani(H),Hin… Cancer Res 1999-04-13

...TSC2/Tsc2 product (tuberin) is not fully understood. To investigate these unsolved problems, we have generated a Tsc2 mu...

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