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Targeting of αv integrin identifies a core molecular pathway that regulates f...

Henderson(Neil C),Arnold(Thomas D),Katamur... Nat Med 2014-02-27

...Pdgfrb (Pdgfrb-Cre) inactivates loxP-flanked genes in mouse HSCs with high efficiency. We used this system to delete the...

An update on primary familial brain calcification.

Lemos(Roberta R),Ferreira(J B M M),Keasey(... Int Rev Neurobiol 2014-07-28

...PDGFRB: c.1973T>C, p.L658P and c.2959C>T, p.R987W, a class III tyrosine kinase receptor. Six other families were found w...

Mutated ephrin receptor genes in non-small cell lung carcinoma and their occu...

Mäki-Nevala(Satu),Kaur Sarhadi(Virinder),T... Genes Chromosomes Cancer 2014-09-05

...PDGFRB, PIK3, PTEN, RET, and TP53 in NSCLC patients. Targeted resequencing was conducted on 81 formalin-fixed, paraffin-...

Neoadjuvant imatinib in advanced primary or locally recurrent dermatofibrosar...

Ugurel(Selma),Mentzel(Thomas),Utikal(Joche... Clin Cancer Res 2014-09-22

...PDGFRB phosphorylation and pigmented-type DFSP were associated with nonresponse. Additional to PDGFRB, the kinases EGFR ...

Genetic aberrations in imatinib-resistant dermatofibrosarcoma protuberans rev...

Hong(Jung Yong),Liu(Xiao),Mao(Mao),Li(Miao... PLoS One 2014-03-25

...PDGFRB inhibition may arise in DFSP, and highlights the usefulness of whole-genome sequencing in identifying drug resist...

Influence of RET mutations on the expression of tyrosine kinases in medullary...

Rodríguez-Antona(Cristina),Muñoz-Repeto(Iv... Endocr Relat Cancer 2014-01-24

...PDGFRB, VEGF (VEGFA), VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4)) by immunohistochemistry in 103 molecularly charact...

Prospective study assessing hypoxia-related proteins as markers for the outco...

Garcia-Donas(J),Leandro-García(L J),Gonzál... Ann Oncol 2014-05-14

...PDGFRB) and P-glycoprotein were assessed by immunohistochemistry in 67 primary ccRCC samples from prospectively recruite...

Making sense of the myelodysplastic/myeloproliferative neoplasms overlap synd...

Tiu(Ramon V),Sekeres(Mikkael A) Curr Opin Hematol 2014-09-25

...PDGFRB, and FGFR1. There are currently no US Food and Drug Administration approved therapies for all MDS/MPN subtypes. A...

Notch signaling is required for the formation of mesangial cells from a strom...

Boyle(Scott C),Liu(Zhenyi),Kopan(Raphael) Development 2014-02-25

...Pdgfrb-positive VSMCs do not enter the vascular cleft and cannot rescue the mesangial deficiency. Notch1 and Notch2 act ...

Identification of gene expression profile of neural crest-derived cells isola...

Takahashi(Masahiro),Suzawa(Tetsuo),Yamada(... Biochem Biophys Res Commun 2014-05-22

...Pdgfrb were expressed at lower levels. Furthermore, DNA microarray analysis showed that GFP-positive cells were positive...

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