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Association of CD16hiCD62Llo Neutrophils with Disease Severity and Impact of SY…

Yao(X),Teague(HL),Knabe(LE),Santana da Cruz(… J Inflamm Res 2026-00-00

...SYK inhibition. These data suggest that CD16hi/CD62Llo neutrophils may contribute to sepsis pathogenesis and that SYK is...

Integrated analyses of single-cell transcriptome and mendelian randomization re…

Cai(HX),Ma(GP),Jia(Z),Liu(FY),Wu(G),Lu(RZ),Z… J Geriatr Cardiol 2026-07-28

...SYK pathway. Additionally, in vitro results demonstrated that CD74 impairs lymphangiogenesis by inducing pyroptosis. Thi...

Sinomenine modulates an MGAT3-associated B-cell IgG N-glycosylation pathway lin…

Liu(P),Zhang(J),Wang(J),Li(R),Tian(R),Wang(S… Pharmacol Res 2026-09-14

...Syk/NF-κB signaling with increased TNF-α, IL-6, and IL-1β. Mechanistically, sinomenine (SIN) bound to MGAT3, as supporte...

Multi-omics integration reveals macrophage polarization and ferroptosis as key …

Qiao(ZJ),Wang(MM),Luo(WS),Yu(BL),Liu(T),Zhu(… Front Immunol 2026-00-00

...SYK, LCK, IL4I1) specifically enriched in macrophages. Macrophages were stratified into high-inflammatory and low-inflam...

INPP5K limits PtdIns (4,5)P2 accumulation in CD19 microclusters and restrains C…

Moës(B),Mostafa(A),Malempré(R),Renson(O),Pie… Front Immunol 2026-00-00

...SYK) were unchanged or reduced. INPP5K deficiency also increased basal CD19 and BCR microcluster formation, impaired CD1...

Syk Inhibition Sensitizes Skin Squamous Carcinoma Cells to TRAIL-Induced Apopto…

Lu(PH),Chiu(LY),Wang(JY),Hsiao(PF),Lu(PH),Hu… Exp Dermatol 2026-09-00

...Syk inhibition or Syk silencing. Combination treatment with TRAIL and Syk inhibitors increased annexin V positivity and ...

Ethanol extract of Liriodendron tulipifera leaves displays anti-inflammatory ac…

Cho(AY),Lim(HK),Lee(JH),Ju(YW),Son(YK),Lee(S… J Ethnopharmacol 2026-01-30

...Syk and Src. Lt-EE significantly ameliorated inflammation in both LPS-induced peritonitis and HCl/EtOH-induced gastritis...

Integrative bioinformatics and transcriptomic analysis identifies biomarkers in…

Senthilkumar(H),Arumugam(M) J Steroid Biochem Mol Biol 2026-01-00

...SYK, TLR2, FCGR3B were identified as crucial nodes using Cytohubba plugins in Cytoscape, highlighting their potential ro...

The impact of sarcopenia on prognosis and fruquintinib efficacy in advanced col…

Wang(Y),Meilu(D),Qi(S),Yufei(T),Song(G),Susu… Front Immunol 2025-00-00

...SYK) gene is a key factor in the occurrence of sarcopenia associated with the use of fruquintinib. Sarcopenia could be a...

Chemical Proteomics Identifies RBBP7 as a New E3 Ligase Supporting Targeted Pro…

Liu(Y),Yang(T),Huang(L),Li(S),Liu(T),Tan(Y),… Angew Chem Int Ed Engl 2025-09-01

...Syk, AKT, and GSK-3β, further highlighting the general feasibility of this approach. Importantly, the ynamide-containing...

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