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Localization of putative tumor suppressor loci by genome-wide allelotyping in h…

Chung(D C),Brown(S B),Graeme-Cook(F),Tillots… Cancer Res 1998-09-17

...TSC2 (16p13), and NF2 (22q12), but no known tumor suppressor gene localizes to 3q27. The mean fractional allelic loss am...

Biallelic mutations of the Tsc2 gene in chemically induced rat renal cell carci…

Satake(N),Urakami(S),Hirayama(Y),Izumi(K),Hi… Int J Cancer 1998-09-14

...TSC2) predisposing gene in the Eker rat model. In this study, we searched for mutations of the Tsc2 gene in chemically i...

Estrogen treatment enhances hereditary renal tumor development in Eker rats.

Wolf(D C),Goldsworthy(T L),Donner(E M),Harde… Carcinogenesis 1998-12-23

...Tsc2) heterozygous mutant (Eker) rats in which a germline mutation predisposes the animals to renal cell tumor developme...

Identification of cDNAs induced by the tumor suppressor Tsc2 gene using a condi…

Orimoto(K),Tsuchiya(H),Sakurai(J),Nishizawa(… Biochem Biophys Res Commun 1998-07-31

...Tsc2 to activate signal transduction and transcription suggests that genes induced by Tsc2 may mediate its biological ro...

Polymorphism in the 5' flanking region of the human somatostatin receptor subty…

Sasi(R),Puebla(L),Khare(S),Patel(Y C) Gene 1998-08-31

...TSC2). Analysis of the 5' flanking region of the hSSTR5 gene has revealed consensus sequences for a number of transcript...

Loss of heterozygosity in the tuberous sclerosis gene associated regions in ade…

Suzuki(K),Ogura(T),Yokose(T),Nagai(K),Mukai(… Int J Cancer 1998-08-17

...TSC2-associated loci was observed more frequently in cases with well-differentiated adenocarcinoma (p = 0.086) and assoc...

Tctex3, related to Drosophila polycomblike, is expressed in male germ cells and…

Kawakami(S),Mitsunaga(K),Kikuti(Y Y),Ando(A)… Mamm Genome 1998-12-31

...Tsc2 gene on mouse Chromosome (Chr) 17, and HUTEX3 was located closely to HSET gene in the HLA class II region of chromo...

Hamartin, the product of the tuberous sclerosis 1 (TSC1) gene, interacts with t…

Plank(T L),Yeung(R S),Henske(E P) Cancer Res 1998-11-18

...TSC2. Tuberin, the product of TSC2, appears to be localized to the Golgi apparatus and may have a function in vesicular ...

Tuberous sclerosis-related gene expression in normal and dysplastic brain.

Vinters(H V),Kerfoot(C),Catania(M),Emelin(J … Epilepsy Res 1998-12-29

...TSC2 (on chromosome 16p13.3) encodes the protein tuberin and TSC1 (on 9q34) encodes hamartin. Tuberin has been immunoloc...

Specific induction of hepatocellular adenomas by transplacental administration …

Fukuda(T),Mitani(H),Tsutsumi(M),Konishi(Y),H… Int J Oncol 1998-12-09

...Tsc2). We document the effect of transplacental administration of N-ethyl-N-nitrosourea to Eker (Eker/+) and non-Eker (+...

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