...TSC2, has been cloned, although its function remains speculative. The identification of the TSC1 gene on chromosome 9q, ...
...TSC2) gene, and predisposition to tumor development is inherited in an autosomal dominant fashion. Uterine and/or cervic...
...Tsc2) gene. We now describe a germline mutation in the gene encoding Tsc2 caused by the insertion of an approximately 5 ...
...TSC2) encodes a 5.5-kb transcript that is widely expressed. The TSC2 gene product, named tuberin, is a 1784-amino-acid p...
...TSC2) gene gives rise to the dominantly inherited cancer in the Eker rat model. The function of the TSC2/Tsc2 gene produ...
...TSC2). The TSC2 gene has recently been isolated, while the TSC1 gene has been mapped to a 5-cM region between the marker...
...TSC2 on 16p13. Loss of heterozygosity (LOH) at the TSC1 and TSC2 loci in lesions from TSC patients has recently been rep...
We have recently identified on rat chromosome 10q a germline mutation in the tuberous sclerosis gene (Tsc2), the gene pr...
...Tsc2) gene. We examined the pattern and frequency of LOH at the predisposing locus in 77 primary tumors and cell lines t...
...Tsc2) gene. In this study, we have identified and characterized a full-length rat intracisternal A-particle (IAP) elemen...
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