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World Health Organization-defined eosinophilic disorders: 2014 update on diag...

Gotlib(Jason) Am J Hematol 2014-06-04

...PDGFRB, or FGFR1', chronic eosinophilic leukemia, not otherwise specified" (CEL, NOS), lymphocyte-variant HE, and idiopa...

Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma.

Sun(Chong),Wang(Liqin),Huang(Sidong),Heyne... Nature 2014-04-22

...PDGFRB), which confer resistance to BRAF and MEK inhibitors. Expression of EGFR in melanoma or treatment with TGF-β resu...

High IGF2 and FGFR3 are associated with tumour progression in undifferentiate...

Rüping(Katinka),Altendorf-Hofmann(Annelore... J Cancer Res Clin Oncol 2014-09-02

...PDGFRB (39 %), FGFR1 (8 %), EGFR (5 %), KDR/VEGFR2 (3 %), ALK (0 %) and high Ki67 (63 %) in UPS. High expressions of IGF...

Identification and functional characterization of imatinib-sensitive DTD1-PDG...

Gosenca(Darko),Kellert(Beate),Metzgeroth(G... Genes Chromosomes Cancer 2014-09-12

...PDGFRB. LDI-PCR revealed a fusion between CCDC88C exon 25 and PDGFRB exon 11 in the case with t(5;17;14)(q33;q11;q32) wh...

Medial prefrontal cortex: genes linked to bipolar disorder and schizophrenia ...

Eisinger(Brian E),Driessen(Terri M),Zhao(C... Front Behav Neurosci 2014-04-25

...Pdgfrb), and nuclear receptor subfamily 1, group D, member 1 (Nr1d1). RT-qPCR confirmed these gene changes as well as FM...

ALK gene aberrations and the JUN/JUNB/PDGFR axis in metastatic NSCLC.

Berghoff(Anna Sophie),Birner(Peter),Streub... APMIS 2014-11-21

...PDGFRB) via JUN and transcription factor Jun B (JUNB) in ALCL. PDGFRB inhibition has been identified as therapy option f...

Integrin-α5β1 is not required for mural cell functions during development of ...

Turner(Christopher J),Badu-Nkansah(Kwabena... Dev Biol 2014-09-19

...Pdgfrb-Cre transgenic mouse line, leads to oedema, haemorrhage and increased levels of embryonic lethality. Unexpectedly...

Chronic neutrophilic leukemia 2014: Update on diagnosis, molecular genetics, ...

Elliott(Michelle A),Tefferi(Ayalew) Am J Hematol 2014-09-18

...PDGFRB, or FGRF1 rearrangements and no identifiable cause for physiologic neutrophilia or, if present, demonstration of ...

Molecular profiling of soft tissue sarcomas using next-generation sequencing:...

Jour(George),Scarborough(John D),Jones(Rob... Hum Pathol 2014-09-22

...PDGFRB, EPHA5, KDM6A, NF1, and FLT4 genes, were also identified. NGS is useful in identifying targetable mutations in so...

Patients with myeloid malignancies bearing PDGFRB fusion genes achieve durabl...

Cheah(Chan Y),Burbury(Kate),Apperley(Jane ... Blood 2014-08-14

Myeloid neoplasms and eosinophilia with rearrangements of PDGFRB are uncommon Philadelphia-negative myeloproliferative n...

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