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Ganoderma lucidum spore oil alleviates psychological stress-evoked tumor progre…

Li(DD),Li(ZX),Zhou(YF),Jin(L),Liang(WL),Xu(W… Chin Med 2025-07-14

...SYK-mediated macrophage phagocytosis pathway was confirmed by qPCR, Western blotting, and confocal laser technology. Our...

Tumor-instructed glutamine synthesis in cancer-associated fibroblasts promotes …

Li(X),Møller(SH),Park(J),Chuang(YM),Hsueh(PC… J Exp Med 2025-09-01

...Syk, and NF-κB in fibroblasts, leading to inflammatory CAF polarization and IL-6-induced glutamine synthesis. These find...

Uptake system of lignin-derived aromatic acids in promising Sphingomonadaceae s…

Fujita(M),Hirano(R),Nagayoshi(K),Kamimura(N)… Sci Rep 2025-07-02

...SYK-6 can catabolize various lignin-derived aromatic compounds that can be used for this purpose. PcaK (Sl-PcaK), a memb...

DOT1L suppressed the proliferation of osteosarcoma cell line via modulating SYK…

Hu(F) Sci Rep 2025-07-02

...SYK, EGFR, p-SYK, p-EGFR, p-STING, p-TBK1, p-IRF3, P53, NLRP3, IL-1β, GSDMD, and apoptosis in Saos-2 cells, while inhibi...

Krylov Spread Complexity as Holographic Complexity beyond Jackiw-Teitelboim Gra…

Heller(MP),Papalini(J),Schuhmann(T) Phys Rev Lett 2025-10-10

...SYK) model and the complexity = volume proposal in classical Jackiw-Teitelboim gravity. Our Letter utilizes the recent c...

Successful Salvage Treatment With Fostamatinib for an Adolescent Patient With R…

Nishizawa(M),Sakamoto(K),Saito(S),Nakazawa(Y) Cureus 2025-09-00

...Syk) signaling. FOS is approved for the treatment of cITP in adults but has not been approved for pediatric and adolesce...

Fc gamma receptor IIa signaling from spinal cord astrocytes promotes neuropathi…

Lacagnina(MJ),Willcox(KF),Fiore(NT),Grieco(A… J Pain 2025-11-00

...Syk) or nuclear factor-κB (NF-κB). These data suggest that FcγRIIa expressed by spinal astrocytes are activated followin...

Cinnamaldehyde triggers cell wall remodeling and enhances macrophage-mediated p…

Shi(Z),Lin(J),Li(W),Chen(F),Zhang(W),Yang(Y)… Front Cell Infect Microbiol 2025-00-00

...Syk/CARD9/NF-κB cascade, leading to elevated pro-inflammatory cytokine secretion. Mechanistically, CIN induces β-1,3-glu...

P-Rex1 controls phagocytosis and the killing of bacteria by murine neutrophils …

Islam(P),Chu(JY),Chetwynd(SA),Walker(R),Hawk… Front Immunol 2025-00-00

...Syk. Recently identified adaptor functions of P-Rex1 in GPCR trafficking and glucose uptake do not seem to underlie its ...

AI-Assisted Discovery and Optimization of Small Molecule TREM2 Agonists with Fu…

Cho(S),Szalai(TV),El Gaamouch(F),Bajusz(D),K… bioRxiv 2025-09-17

...SYK phosphorylation in TREM2-expressing cells, and promoted microglial phagocytosis. Together, these findings establish ...

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