...TSC2 genes, encoding hamartin and tuberin, respectively. The clinical picture of the disease is connected with the forma...
...Tsc2 (EEF Tsc2(-/-)) produced 28 times as much MCP-1 protein as did EEF Tsc2(+/+) cells; transient expression of WT but ...
...TSC2-is the cause of this syndrome, with TSC2 mutations accounting for 80-90% of all mutations. Molecular diagnosis of T...
...TSC2. Hamartin and tuberin, the products of TSC1 and TSC2, respectively, form heterodimers and inhibit the mammalian tar...
...Tsc2 in ERC-18 cells and compared the effect of Tsc2 expression on apoptotic induction. Tsc2 expression increased the su...
...TSC2 gene on chromosome 16p13.3. Here we describe a deletion encompassing the TSC1 gene and two neighboring transcripts ...
...TSC2. Here, we review recent advances in our understanding of the growth and signaling functions of the TSC1 and TSC2 pr...
...TSC2. TOR multimerization thus partially accounts for the high apparent molecular weight of TOR complexes and offers nov...
...TSC2 genes. TSC starts in early childhood and is characterized by cerebral hamartomas (benign tumours), severe epilepsy ...
...TSC2) that can be of autosomal dominant inheritance or spontaneous mutation.
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