...TSC2 genotypic pattern or multiple extrarenal manifestations. Angiomyolipomas were the most common lesions (11 patients)...
...TSC2 markers was detected. This case illustrates that LAM can be diagnosed by the identification of LCC without an invas...
...Tsc2 gene, and the wild-type rats (Tsc2(+/+)), a noncarrier counterpart. We found that Tsc2(+/EK), but not Tsc2(+/+), SM...
...TSC2), mammalian target of rapamycin (mTOR), 4E-binding protein-1 (4E-BP1), ribosomal protein S6 kinase (S6K1), or eukar...
The tuberous sclerosis complex (TSC) proteins TSC1 and TSC2 regulate protein translation by inhibiting the serine/threon...
Tuberous sclerosis (TSC) is a hamartoma syndrome caused by mutations in TSC1 or TSC2 in which cerebral cortical tubers a...
...TSC2 can be reversed by treatments with rapamycin or the readdition of TSC2. Our work explains why human cancers with ab...
...TSC2 genes result in mTOR-signaling activity. Here, we addressed whether Pi3K-pathway activation differentiates balloon ...
...TSC2) and their gene products (hamartin and tuberin, respectively), revealed that they function together as a complex. H...
...TSC2 germline mutations were not detected at DNA analysis.,This article indicates that occurrence of LAM may be possible...
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