...Tsc2 gene mutant), which is a homolog of the human mesothelin/megakaryocyte potentiating factor gene, and a novel ELISA ...
...TSC2. In these settings, GSK3 phosphorylation is sensitive to mTORC1 inhibition by rapamycin or amino acid withdrawal, a...
...TSC2 (tuberin). The LKB1-->AMPK-->TSC2 pathway negatively regulates the target of rapamycin (TOR), and this appears to b...
...TSC2 gene, although autism can and does develop in children with TSC1 mutations. The likelihood is also greater if the c...
...Tsc2, serves as a GTPase activating protein (GAP) for Rheb, implying Rheb's role in this genetic disorder. Finally, Rheb...
...Tsc2 and TPA. We compared the cellular response of Tsc2-null (ERC-18) and Tsc2-competent (NRK-52E) renal epithelial cell...
...TSC2 tumor suppressor gene. TSC1 and TSC2 products, Harmatin and Tuberin, form the functional complex to serve as the ne...
...TSC2 tumor suppressor complex and the hypoxia-inducible gene REDD1/RTP801. Disruption of the TSC1/TSC2 complex through l...
...TSC2 among others. Comparisons of pubertal and BPH expression profiles revealed a subset of genes that shared the expres...
...TSC2. A key function of these genes is to regulate the mammalian target of rapamycin (mTOR) pathway in response to cellu...
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