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TP53 BRCA1 CRISPR single-cell cancer

Lininger(R A),Zhuang(Z),Man(Y),Park(W S),Emm… Mod Pathol 2000-01-10

...TSC2/PKD1 gene region), 17p13 (TP53), 17q13 (NM23), and 22q12 (D22S683).,Among informative in situ and invasive apocrine...

Yamashita(Y),Ono(J),Okada(S),Wataya-Kaneda(M… Am J Med Genet 2000-03-15

...TSC2 genes, using single-strand conformational polymorphism analysis and direct sequencing. Four possible pathogenic mut...

Astrinidis(A),Khare(L),Carsillo(T),Smolarek(… J Med Genet 2000-02-18

...TSC2. Twelve of the patients had known renal angiomyolipomas. No TSC2 mutations were detected. We did find three silent ...

Murthy(V),Haddad(L A),Smith(N),Pinney(D),Tys… Am J Physiol Renal Physiol 2000-06-12

...TSC2 genes, coding hamartin and tuberin, respectively. Immunofluorescence analysis of tuberin and hamartin performed her...

Carsillo(T),Astrinidis(A),Henske(E P) Proc Natl Acad Sci U S A 2000-06-30

...TSC2 loss of heterozygosity in 7 of 13 (54%) of angiomyolipomas from sporadic LAM patients, suggesting that LAM and TSC ...

Pasumarthi(K B),Nakajima(H),Nakajima(H O),Ji… Circ Res 2000-06-20

...TSC2-deficient cells. Surprisingly, targeted expression of the most potent TSC2 cDNA to the heart did not perturb cardia...

Mizuguchi(M),Takashima(S),Yamanouchi(H),Naka… J Neuropathol Exp Neurol 2000-04-07

...Tsc2 gene. We describe here histological and immunohistochemical findings of the brain lesions in Eker rats, with emphas...

Jónasdóttir(T J),Mellersh(C S),Moe(L),Heggeb… Proc Natl Acad Sci U S A 2000-05-17

...TSC2) and the tumor suppressor gene TP53. These data suggest that RCND may be caused by a previously unidentified tumor ...

Jónasdóttir(T J),Mellersh(C S),Moe(L),Vignau… Anim Genet 2000-07-13

The canine tuberous sclerosis 2 (TSC2) gene has been mapped to canine chromosome 6 using a canine whole genome radiation...

Mizuguchi(M),Ikeda(K),Takashima(S) Acta Neuropathol 2000-07-17

...TSC2 gene. The clinical manifestations of mutations of the two genes are hardly distinguishable, for reasons as yet unkn...

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