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SOCS3 in retinal neurons and glial cells suppresses VEGF signaling to prevent...

Sun(Ye),Ju(Meihua),Lin(Zhiqiang),Fredrick(... Sci Signal 2016-06-20

...SOCS3) in neurons and glial cells prevents neovascularization. We found that Socs3 expression was increased in the retin...

SOCS3 Methylation Predicts a Poor Prognosis in HBV Infection-Related Hepatoce...

Zhang(Xin),You(Qingshan),Zhang(Xiaolei),Ch... Int J Mol Sci 2016-07-21

...SOCS3 in HBV infection-related HCC and the relationship between SOCS3 methylation and the clinical outcome remain unknow...

Hypothalamic PKA regulates leptin sensitivity and adiposity.

Yang(Linghai),McKnight(G Stanley) Nat Commun 2016-05-02

...Socs3, is inhibited in the hypothalamus of RIIβ KO mice. During fasting, RIIβ-PKA is activated and this correlates with ...

Interferon lambda inhibits dengue virus replication in epithelial cells.

Palma-Ocampo(Helen K),Flores-Alonso(Juan C... Virol J 2016-06-29

...SOCS3, during DENV-2 infection was associated with reduced IFN-λ1 expression.,Evidence described here suggests that IFN-...

Genes Involved in Maintaining the Bone Marrow Stroma Are Dysregulated in Pati...

Livun(Ana),Newberry(Kate J),Manshouri(Tagh... Anticancer Res 2016-01-04

...SOCS3) was significantly increased.,Patients with primary MF showed aberrant expression of several genes involved in mai...

The role of probiotics in the prevention of severe infections following abdom...

Stavrou(George),Giamarellos-Bourboulis(Eva... Int J Antimicrob Agents 2016-10-06

...SOCS3 gene, which encodes the protein SOCS3 that suppresses cytokine production, implying a direct interaction of probio...

SOCS2: physiological and pathological functions.

Letellier(Elisabeth),Haan(Serge) Front Biosci (Elite Ed) 2016-09-26

...SOCS3 are important regulators of the JAK-STAT pathway. Here, we focus on SOCS2 and review its biological function as we...

Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decre...

Yen(Meng-Chi),Shih(Ying-Chu),Hsu(Ya-Ling),... Oncol Rep 2016-10-28

...SOCS3 expression was induced by isolinderalactone due to inhibiting the microRNA hsa-miR-30c-5p (miR-30c) expression. In...

Exposure to TiO2 Nanoparticles Induces Immunological Dysfunction in Mouse Tes...

Hong(Fashui),Wang(Yajing),Zhou(Yingjun),Zh... J Agric Food Chem 2016-08-11

...SOCS3 (-8.11 to -34.86%), and increased expression of Toll-like receptor (TLR)-3 (21.4-156.03%), TLR-4 (37.0-109.87%), n...

A Kinetic-Model-Based Approach to Identify Malfunctioning Components in Signa...

Li(Xianhua),Ribaudo(Nicholas),Huang(Zuyi J... Biomed Res Int 2016-09-26

...SOCS3. Similarly, the TNF-α/NF-κB model was used to obtain the data in which abnormal oscillation dynamic was shown in t...

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