Literature Search

Miller(WD),Manion(A),Mishra(AK),Sheedy(CJ),B… J Cell Biol 2025-12-01

...Syk phosphorylates the GEF Vav, which activates Rac to drive F-actin rearrangement and target internalization. CD47 inhi...

Oh(EB),Kong(YJ),Kim(T),Jang(J),Yu(H),Park(JW… Sci Rep 2025-10-16

...Syk), linker for the activation of T cells (LAT), vav guanine nucleotide exchange factor 1 (Vav1), and Bruton tyrosine k...

Ditsiou(A),Toffoli(L),Vella(V),D'Este(F),Gag… Cancer Gene Ther 2025-12-00

...SYK is a plausible therapeutic target in GI-NET using two human cell lines. SYK expression in GI-NET cells was confirmed...

Edwards(ESJ),Chatelier(J),Snell(GI),Seo(GH),… J Clin Immunol 2025-10-20

...SYK, and tonic and ligand-induced phospho-S6 levels. Spontaneous SYK autophosphorylation, S6 and p38 phosphorylation wer...

Zhang(Y),Zhang(Y),Dang(H),Zhang(C),He(K),Yan… Front Immunol 2025-00-00

...SYK, TREM-1 triggered the CARD9/NF-κB signaling and induced pyroptosis. SYK inhibition reversed these effects, confirmin...

Shen(Y),Ma(X),Du(Z),Li(Y),Mei(Z),Zhao(L) Pharmaceuticals (Basel) 2025-07-18

...SYK. Molecular docking simulations revealed strong binding affinities between ZHW's primary bioactive constituents (lina...

Huang(M),Jiang(J),Li(YJ),Jiang(MY),Yang(M),D… Sci Rep 2025-07-10

...SYK, MAPK8, CTSB, RAC2, JAK2, TYMS) with high degree values. Furthermore, molecular docking studies confirmed strong bin...

Yao(C),Wang(J) Sci Rep 2025-07-13

...Syk, and p-JNK protein expression consistent with the in vivo results(P < 0.05), where the Syk inhibitor suppressed both...

Chen(H),Xu(Z),Varner(J) Front Immunol 2025-00-00

...Syk, MerTK/Axl, and immune checkpoints such as Trem2, LILRBs, VISTA, and CD40. We examine preclinical and clinical findi...

Costa(A),Mulas(O),Mereu(AM),Schintu(M),Greco… Front Immunol 2025-00-00

...SYK) inhibitors such as fostamatinib and sovleplenib, and phosphoinositide 3-kinase (PI3K) inhibitors such as parsaclisi...