...TSC1) and enhanced metastasis of HCC cells by activating STAT3. Furthermore, DYRK1A promoted EMT by cooperatively activa...
...TSC1. Family members without TSC did not have this mutation. The mutations in the intron regions cannot be ruled out as ...
...Tsc1 in mice is sufficient to induce ASD-like phenotypes. However, despite these functional changes, whether Tsc1 haploi...
...Tsc1, a negative regulator of mTOR, in microglia in mice of both sexes, caused mTOR activation and upregulation of Trem2...
...TSC1 or TSC2 affects multiple developmental processes in the renal epithelial, stromal, and glial compartments. First, T...
...TSC1/2 gene next-generation sequencing (NGS). TSC1/2 mutation types and imaging examinations were screened for combined ...
...TSC1 mutations were exclusively found in preinvasive lesions. Compared with EGFR L858R and exon 19 deletion, patients wi...
...TSC1 or TSC2 genes, encoding hamartin and tuberin, respectively. It is a multisystemic disease, affecting most frequentl...
...TSC1 or TSC2 genes, resulting in benign lesions that involve multiple organs including the central nerves system. A 39-y...
...TSC1 and TSC2) form a complex to inhibit the mammalian target of rapamycin [mTOR; mTOR complex 1 (mTORC1)] pathway. This...
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