...TSC2). There is no common genetic background for HI, but mosaicism of 9q33 locus has been documented. As per our knowled...
...TSC2 mutated in tuberous sclerosis complex (TSC), to be altered in gangliogliomas and FCD with Taylor type balloon cells...
...TSC2. About 80% of affected patients have a new mutation, and the remaining 20% have inherited a TSC gene mutation from ...
...TSC2 tumor suppressors. Insulin stimulates the phosphorylation of S6K1, an mTORC1 substrate, but it is not known how mTO...
...TSC2 or its target, the proto-oncogene Rheb (Ras homologue enriched in brain). Instead, we found that the AA input was m...
...Tsc2-RGH and Tsc2-DRG in Eker rats completely suppressed renal carcinogenesis and rescued homozygous (Tsc2(Ek/Ek)) mutan...
...TSC2, the negative regulators of mTOR, results in dramatic accumulation of p53 and apoptosis in response to stress condi...
...Tsc2-/-) cells than in Tsc2+/+ cells, but unlike human LAM cells, the Tsc2-/- Eker rat cells did not contain CD44v6 spli...
...TSC2, encoding hamartin and tuberin, respectively. TSC is pathologically characterized by the occurrence of multiple ham...
...TSC2 tumour suppressor genes. Studies in Drosophila and other organisms have identified TSC signalling as a conserved pa...
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