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Suppressor of Cytokine Signaling-3 (SOCS-3) Induces Proprotein Convertase Sub...

Ruscica(Massimiliano),Ricci(Chiara),Macchi... J Biol Chem 2016-07-06

...SOCS3 in HepG2 cells (HepG2(SOCS3)) strongly inhibited STAT3 phosphorylation and induced PCSK9 mRNA and protein, with no...

DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and ...

Kalmár(Alexandra),Péterfia(Bálint),Hollósi... BMC Cancer 2016-04-21

...SOCS3) showed hypermethylation and THBS2 showed hypomethylation both in AD and in CRC samples compared to NAT, while BCL...

Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 an...

Kim(Min Soo),Lee(Won Sung),Jeong(Joon),Kim... Oncotarget 2016-09-20

...SOCS3-mediated JAK2 degradation, resulting in increased total JAK2 and STAT3 levels, which subsequently leads to JAK2/ST...

Respiratory Syncytial Virus Nonstructural Proteins Upregulate SOCS1 and SOCS3...

Zheng(Junwen),Yang(Pu),Tang(Yan),Pan(Zishu... J Immunol Res 2016-08-19

...SOCS3, which appeared to be different from autocrine IFN dependent. NS1 induced both SOCS1 and SOCS3 upregulation, while...

The Prognostic Role of SOCS3 and A20 in Human Cholangiocarcinoma.

Wang(Yimin),Wan(Ming),Zhou(Qingxin),Wang(H... PLoS One 2016-06-07

...SOCS3 and A20 in human CCA tissues to assess the prognostic significance of these proteins. The expression of SOCS3 and ...

Combined parental obesity augments single-parent obesity effects on hypothala...

Ornellas(Fernanda),Souza-Mello(Vanessa),Ma... Physiol Behav 2016-09-30

...SOCS3 signaling in the offspring. In addition, maternal obesity elevated inflammatory markers and altered NPY and POMC e...

Hypothyroidism advances mammary involution in lactating rats through inhibiti...

Campo Verde Arboccó(Fiorella),Sasso(Corina... Mol Cell Endocrinol 2016-10-06

...SOCS3, STAT3 and LIF mRNAs, suggesting a decrease in PRL signaling and induction of involution markers. Furthermore, Cas...

Estrogen accelerates the resolution of inflammation in macrophagic cells.

Villa(Alessandro),Rizzi(Nicoletta),Vegeto(... Sci Rep 2016-08-19

...SOCS3 and STAT3 signaling pathways, E2 facilitates the progression of the inflammatory process toward the IL10-dependent...

Excessive eccentric exercise leads to transitory hypothalamic inflammation, w...

Pereira(B C),da Rocha(A L),Pauli(J R),Rope... Neuroscience 2016-09-14

...SOCS3 levels at week eight. The OTR/down, OTR/up and OTR groups exhibited increased IL-10 levels at week 10. The OTR/up ...

Exposure to nicotine increases dopamine receptor content in the mesocorticoli...

Pinheiro(C R),Oliveira(E),Manhães(A C),Fra... Pharmacol Biochem Behav 2016-05-17

...SOCS3 contents in VTA; lower TH, higher D1R, D2R and DAT contents in NAc; higher TH content in DS; and higher D2R and SO...

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