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The ins and outs of getting in: structures and signals that enhance BCR or Fc r…

Shen(L),Lang(M L),Wade(W F) Immunopharmacology 2001-01-18

...Syk, in particular calcium flux and protein kinase C activation, are necessary for MIIC induction. PI(3) kinase is also ...

Globotriaosyl ceramide (CD77/Gb3) in the glycolipid-enriched membrane domain pa…

Mori(T),Kiyokawa(N),Katagiri(Y U),Taguchi(T)… Exp Hematol 2001-01-02

...Syk kinases leading to increased binding of these proteins to surface IgM (sIgM) in Ramos cells after Stx1 treatment. We...

Tumor necrosis factor-alpha activation of the c-Jun N-terminal kinase pathway i…

Avdi(N J),Nick(J A),Whitlock(B B),Billstrom(… J Biol Chem 2001-04-12

...Syk, and activation of a three-part MAPk module composed of MEKK1, MKK7, and/or MKK4 and JNK1. JNK activation was attenu...

Rhodocytin induces platelet aggregation by interacting with glycoprotein Ia/IIa…

Suzuki-Inoue(K),Ozaki(Y),Kainoh(M),Shin(Y),W… J Biol Chem 2001-04-05

...Syk and phospholipase Cgamma2, intracellular Ca(2+) mobilization, and platelet aggregation occur later in a cAMP-sensiti...

Evidence for two distinct epitopes within collagen for activation of murine pla…

Schulte(V),Snell(D),Bergmeier(W),Zirngibl(H)… J Biol Chem 2001-02-08

...Syk, LAT, SLP-76, and phospholipase C gamma 2. In contrast, platelet aggregation and tyrosine phosphorylation of these p...

Regulation of the phospholipase C-gamma2 pathway in B cells.

Kurosaki(T),Maeda(A),Ishiai(M),Hashimoto(A),… Immunol Rev 2001-05-31

...Syk and Btk in PLC-gamma2 activation. Until recently, the molecular mechanism underlying the double requirement for Syk ...

Ligation of HLA-DR molecules on B cells induces enhanced expression of IgM heav…

Tabata(H),Matsuoka(T),Endo(F),Nishimura(Y),M… J Biol Chem 2001-01-04

...Syk inhibitor piceatannol, but not the Src inhibitor PP2 had a marked inhibitory effect on IgM secretion. Furthermore, l...

Negative control of store-operated Ca2+ influx by B cell receptor cross-linking.

Hashimoto(A),Hirose(K),Kurosaki(T),Iino(M) J Immunol 2001-03-08

...Syk- or SHIP (Src homology 2 domain containing phosphatidylinositol 5'-phosphatase)-deficient cells, indicating that Lyn...

Tyrosine phosphorylation of the linker for activator of T cells in mast cells b…

Kimura(T),Hisano(M),Inoue(Y),Adachi(M) Immunol Lett 2001-02-15

...Syk, Btk, and Fak that induce the tyrosine phosphorylation of various proteins. The linker for activation of T cells (LA...

Signal transduction involved in MCP-1-mediated monocytic transendothelial migra…

Cambien(B),Pomeranz(M),Millet(M A),Rossi(B),… Blood 2001-03-15

...Syk kinase, whereas SAPK2/p38 activation was inhibited by PP2, revealing an upstream regulation by Src-like kinases. In ...

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