...Tsc2, molecules linked to the autosomal dominant disease tuberous sclerosis, an increase in the activity of the translat...
...Tsc2 have critical functions in mammalian axon formation and growth. Overexpression of Tsc1/Tsc2 suppresses axon formati...
...TSC2, and others are needed to integrate the external signal within the inside of the cell, as is the case of gene DMPK....
...TSC2 (tuberin), responsible for TSC, identification of several downstream protein cascades that might be affected in TSC...
...tsc2 tumor suppressor genes. TSC1 and TSC2 protein form a physical and functional complex in vivo. Recent studies have d...
...TSC2 (tuberin). Rheb plays a key role in the regulation of cell growth in response to growth factors, nutrients, and ami...
...TSC2, the negative regulators of mTOR, results in dramatic accumulation of p53 and apoptosis in response to stress condi...
...TSC2 (pTSC2), and phospho-S6 (pS6) by immunohistochemistry. We found that Erk-mediated TSC2 phosphorylation occurred at ...
...TSC2 tumor suppressor complex serves as a repressor of the mTOR pathway, and disruption of TSC1/TSC2 complex function ma...
...TSC2, an upstream regulator of mTORC1, at sites that are targets for Akt/PKB. Finally, the activation of overall protein...
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