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Alternative antigen receptor (TCR) signaling in T cells derived from ZAP-70-def…

Noraz(N),Schwarz(K),Steinberg(M),Dardalhon(V… J Biol Chem 2000-06-30

...Syk, are observed in Syk(hi)/ZAP-70(-) T cells. However, Syk(hi)/ZAP-70(-) T cells differ from control T cells with resp...

Characterisation and specificity of two single-chain Fv antibodies directed to …

Péneff(C),Lefranc(M P),Dariavach(P) J Immunol Methods 2000-05-02

...Syk, we screened a human synthetic phage-display library. Two glutathione S-transferase (GST):Syk fusion proteins contai...

Modulation of human neutrophil responses to CD32 cross-linking by serine/threon…

Rollet-Labelle(E),Gilbert(C),Naccache(P H) J Immunol 2000-02-10

...Syk, was observed. After a longer incubation (>5 min) with calyculin, concomitant with an accumulation of serine and thr...

Adapter proteins SLP-76 and BLNK both are expressed by murine macrophages and a…

Bonilla(F A),Fujita(R M),Pivniouk(V I),Chan(… Proc Natl Acad Sci U S A 2000-03-23

...Syk, phospholipase C-gamma2, and extracellular signal regulated kinases 1 and 2, and normal FcgammaR-dependent phagocyto...

Activation of lymphocyte signaling by the R1 protein of rhesus monkey rhadinovi…

Damania(B),DeMaria(M),Jung(J U),Desrosiers(R… J Virol 2000-04-03

...Syk kinase. Expression of a CD8 chimera protein containing the extracellular and transmembrane domains of CD8 fused to t...

Identification of seven genes regulated by wild-type p53 in a colon cancer cell…

Okamura(S),Ng(C C),Koyama(K),Takei(Y),Arakaw… Oncol Res 2000-04-03

...Syk), high mobility group chromosomal protein 17 (HMG-17), transferrin receptor, human alpha-tubulin, and sds22-like pro...

Specificity of alpha-cyano-beta-hydroxy-beta-methyl-n-[4-(trifluoromethoxy)phe …

Ghosh(S),Zheng(Y),Jun(X),Mahajan(S),Mao(C),S… Clin Cancer Res 2000-02-14

...SYK kinase, and the receptor family PTK insulin receptor kinase. This observation is in contrast to the activity of a qu...

Purification and characterization of human Syk produced using a baculovirus exp…

Baldock(D),Graham(B),Akhlaq(M),Graff(P),Jone… Protein Expr Purif 2000-03-09

...syk (Syk) plays an essential role in signaling via a variety of immune and nonimmune cell receptors. Syk is activated in...

Sequential requirements of the N-terminal palmitoylation site and SH2 domain of…

Honda(Z i),Suzuki(T),Kono(H),Okada(M),Yamamo… Mol Cell Biol 2000-03-16

...Syk and its recruitment to FcepsilonRI. These findings suggest that Lyn and Fyn could, but c-Src could not, drive Fcepsi...

Purification of a 72-kDa protein-tyrosine kinase from rat liver and its identif…

Tsuchida(S),Yanagi(S),Inatome(R),Ding(J),Her… J Biochem 2000-05-31

...Syk or Syk-related PTK in non-hematopoietic tissues. In this study, we have purified from blood cell-depleted rat liver ...

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