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The tyrosine kinases p53/56lyn and p72syk are differentially expressed at the p…

Lavens-Phillips(S E),MacGlashan(D W) Am J Respir Cell Mol Biol 2000-11-03

...syk kinase were found for both groups. By sequencing a critical region in the syk mRNA, our results also demonstrate tha...

Interaction of linker for activation of T cells with multiple adapter proteins …

Asazuma(N),Wilde(J I),Berlanga(O),Leduc(M),L… J Biol Chem 2000-11-24

...Syk was provided by studies on Syk-deficient platelets. The increase in phosphorylation of the FcR gamma-chain is associ...

Engagement of the human pre-B cell receptor generates a lipid raft-dependent ca…

Guo(B),Kato(R M),Garcia-Lloret(M),Wahl(M I),… Immunity 2000-09-25

...Syk, BLNK, PI3K, Btk, VAV, and PLCgamma2. Formation of this module was essential for pre-BCR calcium signaling. Together...

The LMP2A ITAM is essential for providing B cells with development and survival…

Merchant(M),Caldwell(R G),Longnecker(R) J Virol 2000-10-04

...Syk and Lyn, blocking B-cell receptor (BCR) signaling and viral lytic replication. SH2 domains in Syk mediate binding to...

Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide pro…

McDonald(D R),Brunden(K R),Landreth(G E) J Neurosci 1999-02-25

...Syk, and FAK were activated on exposure of microglia and THP1 monocytes to Abeta, resulting in the tyrosine kinase-depen...

Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role fo…

Lupher(M L),Rao(N),Lill(N L),Andoniou(C E),M… J Biol Chem 1999-02-03

...Syk Tyr323 in the negative regulation of Syk. Co-expression of Cbl with Syk in COS-7 cells led to a dose-dependent decre...

Induction of the antigen receptor expression on B lymphocytes results in rapid …

Zhang(Y),Wienands(J),Zürn(C),Reth(M) EMBO J 1999-02-16

...Syk, and the phosphorylation of several substrate proteins including HS1 and SLP-65. How these signaling elements are co...

Interdomain B in ZAP-70 regulates but is not required for ZAP-70 signaling func…

Zhao(Q),Williams(B L),Abraham(R T),Weiss(A) Mol Cell Biol 1999-02-10

...Syk-deficient DT-40 B cells and ZAP-70/Syk-deficient Jurkat cells. Here we show that Delta still utilizes the same pathw...

Genetic and biochemical characterization of a 2-pyrone-4, 6-dicarboxylic acid h…

Masai(E),Shinohara(S),Hara(H),Nishikawa(S),K… J Bacteriol 1999-02-05

...SYK-6 on vanillic acid but is not responsible for the growth of SYK-6 on syringic acid.

The Syk family of protein tyrosine kinases in T-cell activation and development.

Chu(D H),Morita(C T),Weiss(A) Immunol Rev 1999-03-22

...Syk family. The two Syk family members expressed in T cells, Syk and ZAP-70, are structurally similar but are expressed ...

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