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Lyn dissociation from phosphorylated Fc epsilon RI subunits: a new regulatory s…

Ortega(E),Lara(M),Lee(I),Santana(C),Martinez… J Immunol 1999-01-21

...Syk, which binds gamma-phospho-immunoreceptor tyrosine-based activation motifs and initiates cellular responses. We stud...

Activation of three classes of nonreceptor tyrosine kinases following Fc gamma …

Pan(X Q),Darby(C),Indik(Z K),Schreiber(A D) Clin Immunol 1999-03-05

...Syk. Here we identify one of the proteins in the 115- to 165-kDa cluster as FAK, a protein tyrosine kinase localized to ...

Interleukin-4 overcomes the negative influence of cyclic AMP accumulation on an…

Venkataraman(C),Chelvarajan(R L),Cambier(J C… Mol Immunol 1999-02-02

...syk. Moreover, BCR mediated tyrosine phosphorylation of PLC gamma2 and CD19 were also unaffected by cAMP accumulation. T...

Phosphorylation- and activation-independent association of the tyrosine kinase …

Fernandez(J A),Keshvara(L M),Peters(J D),Fur… J Biol Chem 1999-02-11

...Syk protein-tyrosine kinase and the phosphorylation of tubulin on tyrosine. To explore the requirement of Syk catalytic ...

Protein tyrosine kinase activity in T lymphocytes from patients with systemic l…

Blasini(A M),Brundula(V),Paris(M),Rivas(L),S… J Autoimmun 1999-01-25

...syk family, was comparable in both groups. However, p59(fyn) immuno-precipitates obtained from unstimulated peripheral b...

DAP12-mediated signal transduction in natural killer cells. A dominant role for…

McVicar(D W),Taylor(L S),Gosselin(P),Willett… J Biol Chem 1999-01-08

...Syk and Zap-70, ligation of Ly49D leads to activation of Syk but not Zap-70. Consistent with this observation, Ly49D/DAP...

Interdomain B in ZAP-70 regulates but is not required for ZAP-70 signaling func…

Zhao(Q),Williams(B L),Abraham(R T),Weiss(A) Mol Cell Biol 1999-02-10

...Syk-deficient DT-40 B cells and ZAP-70/Syk-deficient Jurkat cells. Here we show that Delta still utilizes the same pathw...

Genetic and biochemical characterization of a 2-pyrone-4, 6-dicarboxylic acid h…

Masai(E),Shinohara(S),Hara(H),Nishikawa(S),K… J Bacteriol 1999-02-05

...SYK-6 on vanillic acid but is not responsible for the growth of SYK-6 on syringic acid.

The Syk family of protein tyrosine kinases in T-cell activation and development.

Chu(D H),Morita(C T),Weiss(A) Immunol Rev 1999-03-22

...Syk family. The two Syk family members expressed in T cells, Syk and ZAP-70, are structurally similar but are expressed ...

Identification of a novel integrin signaling pathway involving the kinase Syk a…

Miranti(C K),Leng(L),Maschberger(P),Brugge(J… Curr Biol 1999-02-08

...Syk.,. Multiple proteins were found to be activated by Syk, downstream of engagement of the platelet/megakaryocyte-speci...

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