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Beta2-integrin, LFA-1, and TCR/CD3 synergistically induce tyrosine phosphorylat…

Tabassam(F H),Umehara(H),Huang(J Y),Gouda(S)… Cell Immunol 1999-06-01

...Syk associated with FAK. These results indicate, for the first time, that signals mediated by LFA-1 can regulate FAK, su...

Phosphorylation of CD19 Y484 and Y515, and linked activation of phosphatidylino…

Buhl(A M),Cambier(J C) J Immunol 1999-05-06

...Syk tyrosine kinases, and perhaps by phosphatidylinositol 3,4,5-trisphosphate, BCR-coupled signaling pathways leading to...

Suboptimal cross-linking of antigen receptor induces Syk-dependent activation o…

Li(H L),Davis(W),Puré(E) J Biol Chem 1999-04-27

...Syk-dependent and is mediated by protein kinase C and phosphoinositol 3-kinase. Moreover, the activation of p70(S6k) res...

Cross-linking of the B cell receptor induces activation of phospholipase D thro…

Hitomi(T),Yanagi(S),Inatome(R),Yamamura(H) FEBS Lett 1999-04-20

...Syk-, Btk- and phospholipase C (PLC)-gamma2-dependent pathway in DT40 cells. Activation of PLD upon BCR engagement is co...

Role for the Rac1 exchange factor Vav in the signaling pathways leading to NK c…

Galandrini(R),Palmieri(G),Piccoli(M),Frati(L… J Immunol 1999-04-13

...Syk. Vav tyrosine phosphorylation is also observed following the activation of NK cells through the low-affinity Fc rece...

Sequential activation of different Ca2+ entry pathways upon cholinergic stimula…

Camello(C),Pariente(J A),Salido(G M),Camello… J Physiol 1999-06-29

...Syk tyrosine kinase, inhibited CCE during ACh decay but not during Ca2+ reintroduction. 3. Simultaneous detection of Mn2...

Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dep…

Williams(B L),Irvin(B J),Sutor(S L),Chini(C … EMBO J 1999-06-01

...Syk play pivotal roles in the coupling of T-cell antigen receptor (TCR) stimulation to the activation of downstream sign...

Thermodynamic study of the binding of the tandem-SH2 domain of the Syk kinase t…

Grucza(R A),Fütterer(K),Chan(A C),Waksman(G) Biochemistry 1999-05-07

...Syk (Syk-tSH2) to a dually phosphorylated peptide derived from the ITAM of the T cell receptor CD3-epsilon subunit. The ...

Phosphatidylinositol 3'-kinase and tyrosine-phosphatase activation positively m…

Lagrue(A H),Francischetti(I M),Guimarães(J A… FEBS Lett 1999-06-01

...Syk and PLCgamma2, but blocked collagen-induced platelet aggregation as well as tyrosine phosphorylation of PLCgamma2. I...

Analysis of tyrosine phosphorylation-dependent interactions between stimulatory…

Yohannan(J),Wienands(J),Coggeshall(K M),Just… J Biol Chem 1999-07-15

...Syk. The results obtained indicate that the protein tyrosine kinase Syk interacts with multiple CD22-derived phosphopept...

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