...TSC2, can be mutated, resulting in the tuberous sclerosis complex phenotype. The protein products of the tuberous sclero...
...TSC2 (tuberin) genes. Tubers are cortical developmental malformations in patients with tuberous sclerosis complex that a...
...TSC2, result in a similar disease phenotype by disrupting the normal interaction of their protein products, hamartin and...
...Tsc2 complex in Drosophila and could negatively regulate Tsc1.Tsc2 activity. Based on genetic studies, HIW has been impl...
...TSC2), a tumor suppressor gene, has been associated with a growth-promoting effect of E2. We hypothesized that tuberin, ...
...TSC2)-affected patients. We developed a microarray consisting of degenerate oligonucleotide primer (DOP)-PCR products fr...
Tuberous sclerosis complex (TSC) is a genetically heterogeneous disease caused by mutations of TSC1 or TSC2 genes. It in...
...tsc2 strains. Deletion of tsc1(+) or tsc2(+) also caused a defect in conjugation. When a limited number of the cells wer...
TSC2, or tuberin, is the product of the tuberous sclerosis tumor suppressor gene TSC2 and acts downstream of the phospha...
...TSC2, both of which are tumor suppressor genes. Hamartin, the protein product of TSC1, was found to interact with the ez...
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