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SYK overexpression enhances microtubule instability in an MDA-MB-231-derived pa…

Kuo(HH),Huang(CW),Chiang(WR),Fang(CT),Liu(SY… Biochim Biophys Acta Mol Cell… 2025-12-00

...SYK), and inhibition or depletion of SYK in the T50R cells cultured without paclitaxel restored MT stability, reduced sp...

Fc gamma receptor IIa signaling from spinal cord astrocytes promotes neuropathi…

Lacagnina(MJ),Willcox(KF),Fiore(NT),Grieco(A… J Pain 2025-11-00

...Syk) or nuclear factor-κB (NF-κB). These data suggest that FcγRIIa expressed by spinal astrocytes are activated followin...

Quantitative Phosphoproteomic Analysis of Testes from Iqcn-Deficient Mice Highl…

Dai(J),Lou(L),Wang(X),Huang(Y),Lei(J),Tang(F… J Proteome Res 2025-09-05

...SYK tyrosine kinases are important for sperm motility and progressive motility. In summary, this study reveals that the ...

Phosphatidylethanolamine is a phagocytic ligand implicated in the binding and r…

Kavianpour(AA),Ghasempour(S),Meyer(KJ),Le(T)… Curr Biol 2025-09-08

...Syk). For bacteria, which contain PE but largely lack PS in their membranes, we report that PE engagement enabled the bi...

Inhibition of Dectin-1 alleviates inflammation in early diabetic retinopathy by…

Sang(W),Zhang(X),Hu(Q),Jiang(B),Guan(J),Huan… Gene 2025-09-05

...Syk), both in vitro and in vivo. In summary, our research strongly suggests that Dectin-1 plays a crucial pro-inflammato...

Development of CRISPR/Cas9-mediated CD16b-/- and CD32a-/- promyelocytic cell li…

Cruz-Cárdenas(JA),López-Arredondo(A),Cázares… Front Immunol 2025-00-00

...SYK phosphorylation, and cytokine responses. Both CD16b-/- and CD32a-/- HL-60-derived clones maintained neutrophilic dif...

Proteomic and Phosphoproteomic Characteristics of the Retina, Choroid, and Scle…

Song(Y),Xu(Z),Li(HT),Xie(Y),Zhao(L),Feng(J),… Mol Cell Proteomics 2025-11-00

...SYK and BTK, along with increased NF-κB, p65, and IL-1β levels in the choroid, indicated enhanced inflammatory responses...

Deciphering opsonized zymosan-induced phosphorylation of p47phox and NADPH oxid…

Liu(J),Pintard(C),Thieblemont(N),Dang(PM),El… Blood 2025-09-25

...Syk), phosphoinositide 3-kinase (PI3K), phospholipase C (PLC), phospholipase D (PLD), Ca2+, and protein kinase C beta 2 ...

Betulinic Acid Inhibits Collagen-Induced Platelet Adhesion and Activation Throu…

Ragupathy(H),Anjum(S),Kuttapan(AE),Maria(G),… Cureus 2025-09-00

...SYK phosphorylation by inhibiting protein tyrosine kinase SYK in flow cytometry studies. Further, it inhibited the plate...

Discovery of platelet glycoprotein VI receptor antagonists and their neuroprote…

Siddiqui(MA),Saraf(P),Shrivastava(SK),Penuma… 3 Biotech 2025-10-00

...Syk tyrosine kinase expression, a marker of platelet activation, via GPVI stimulation, as confirmed through flow cytomet...

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