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Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dep…

Williams(B L),Irvin(B J),Sutor(S L),Chini(C … EMBO J 1999-06-01

...Syk play pivotal roles in the coupling of T-cell antigen receptor (TCR) stimulation to the activation of downstream sign...

Activation of protein kinase C is required for the stable attachment of adheren…

Polanowska-Grabowska(R),Gear(A R) Arterioscler Thromb Vasc Biol 1999-12-27

...syk) were not influenced by the PKC inhibitors, whereas adhesion to polylysine was prevented. These results indicate tha...

Molecular consequences of human mast cell activation following immunoglobulin E…

Reischl(I G),Coward(W R),Church(M K) Biochem Pharmacol 1999-12-22

...syk. For the purposes of description, the subsequent events may be grouped in three cascades characterized by the key pr...

Cross-linking of the B cell receptor induces activation of phospholipase D thro…

Hitomi(T),Yanagi(S),Inatome(R),Yamamura(H) FEBS Lett 1999-04-20

...Syk-, Btk- and phospholipase C (PLC)-gamma2-dependent pathway in DT40 cells. Activation of PLD upon BCR engagement is co...

A direct interaction between the adaptor protein Cbl-b and the kinase zap-70 in…

Zhang(Z),Elly(C),Qiu(L),Altman(A),Liu(Y C) Curr Biol 1999-04-22

Engagement of the T-cell receptor (TCR)-CD3 complex induces a rapid increase in the activities of Src-family and Syk/Zap...

Volume expansion stimulates p72(syk) and p56(lyn) in skate erythrocytes.

Musch(M W),Hubert(E M),Goldstein(L) J Biol Chem 1999-04-15

...Syk and Lyn can directly phosphorylate the cytoplasmic domain of band 3. Upon cell volume expansion, Syk activity was in...

Expression of dominant-negative src-homology domain 2-containing protein tyrosi…

Dustin(L B),Plas(D R),Wong(J),Hu(Y T),Soto(C… J Immunol 1999-04-14

...Syk was hyperphosphorylated and hyperactive in B cells expressing SHP-1 (C453S). SHP-1 and Syk were coimmunoprecipitated...

Cutting edge: a role for the adaptor protein LAT in human NK cell-mediated cyto…

Jevremovic(D),Billadeau(D D),Schoon(R A),Dic… J Immunol 1999-04-14

...Syk family protein tyrosine kinases to downstream effectors. However, the mechanisms linking these second messenger path...

Suboptimal cross-linking of antigen receptor induces Syk-dependent activation o…

Li(H L),Davis(W),Puré(E) J Biol Chem 1999-04-27

...Syk-dependent and is mediated by protein kinase C and phosphoinositol 3-kinase. Moreover, the activation of p70(S6k) res...

Role for the Rac1 exchange factor Vav in the signaling pathways leading to NK c…

Galandrini(R),Palmieri(G),Piccoli(M),Frati(L… J Immunol 1999-04-13

...Syk. Vav tyrosine phosphorylation is also observed following the activation of NK cells through the low-affinity Fc rece...

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