...TSC1/2/mTOR/RICTOR mutations or TFE3 translocations were detected in 16 of 31 (52%) cases by NGS. Recurrent ATRX alterat...
...TSC1 patients had a higher prevalence of MMPH than TSC2 patients (24% versus 13%, p = 0.05). Many rare findings (e.g., l...
...TSC1, and TP53 were temporally variable, despite apparent clonal prevalence at one time point. Limitations include the d...
...TSC1, CTH, GCLM, IRS2 and SESN2) whose predicted DR-relatedness remain to be validated in future wet-lab experiments. Th...
...TSC1 or TSC2 genes, leading to hyperactivation of the mechanistic target of rapamycin (mTOR) pathway and subsequent deve...
...TSC1. Considering external verification, this model effectively predicted recurrence-free survival, notably within one y...
...TSC1 mutations were exclusively found in preinvasive lesions. Compared with EGFR L858R and exon 19 deletion, patients wi...
...TSC1, TSC2, VHL. 18 patients undergoing ICI/ICI and ICI/TKI who had tumor tissue adequate for molecular analysis were in...
...TSC1, and TSC2. Endpoints of interests were radiographic progression-free survival (rPFS), time to development of castra...
...TSC1 might be associated with RPI/MNS phenotypes, whereas alterations in PBRM1 might be associated with non-RPI/MNS phen...
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