Literature Search

Veleeparambil(M),Wang(C),Kessler(PM),Sengupt… mBio 2025-11-12

...Syk interacted with TLR9 in a CpG-dependent manner. Activated Syk interacted with TLR9 and was critical for activating T...

Li(W),Qi(Y),Li(Y),Liu(L),Dong(X),Li(B) Front Immunol 2025-00-00

...Syk signaling pathway in TAMs attenuated the invasive and migratory ability of CAL27 cells through promoting M1 polariza...

Ye(S),Wu(C),Huang(S),Fan(H),Zhang(Z),Chen(J)… Genomics 2025-11-00

...Syk-PI3K axis, ultimately disrupting total Leydig cell number and Insl3 expression. Collectively, these findings unveil ...

Islam(P),Chu(JY),Chetwynd(SA),Walker(R),Hawk… Front Immunol 2025-00-00

...Syk. Recently identified adaptor functions of P-Rex1 in GPCR trafficking and glucose uptake do not seem to underlie its ...

Umeda(R),Ito(Y),Minatoguchi(S),Koide(S),Taka… FASEB J 2025-09-30

...Syk phosphorylation, and reduced VEGF secretion in vitro. Our results position KYNA as a key modulator of neutrophil-dri...

Camerlo(S),Radin(M),Rosati(G),Padrini(M),Mon… EJHaem 2025-10-00

...SYK inhibitor. The authors have confirmed clinical trial registration is not needed for this submission.

Xie(B),Ding(L),Zhang(Q),Chen(X),Wang(K),Lv(J… J Proteome Res 2025-10-03

...SYK, CTSS). Functional enrichment and protein-protein interaction (PPI) network analysis highlighted critical pathways i...

Miller(WD),Manion(A),Mishra(AK),Sheedy(CJ),B… J Cell Biol 2025-12-01

...Syk phosphorylates the GEF Vav, which activates Rac to drive F-actin rearrangement and target internalization. CD47 inhi...

Oh(EB),Kong(YJ),Kim(T),Jang(J),Yu(H),Park(JW… Sci Rep 2025-10-16

...Syk), linker for the activation of T cells (LAT), vav guanine nucleotide exchange factor 1 (Vav1), and Bruton tyrosine k...

Ditsiou(A),Toffoli(L),Vella(V),D'Este(F),Gag… Cancer Gene Ther 2025-12-00

...SYK is a plausible therapeutic target in GI-NET using two human cell lines. SYK expression in GI-NET cells was confirmed...