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Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathwa…

Fütterer(K),Wong(J),Grucza(R A),Chan(A C),Wa… J Mol Biol 1998-09-16

...Syk family of kinases, consisting of ZAP-70 and Syk, play essential roles in a variety of immune and non-immune cells. T...

BLNK: a central linker protein in B cell activation.

Fu(C),Turck(C W),Kurosaki(T),Chan(A C) Immunity 1998-09-01

...Syk tyrosine kinase with PLCgamma, the Vav guanine nucleotide exchange factor, and the Grb2 and Nck adapter proteins. Ty...

The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in …

Kiefer(F),Brumell(J),Al-Alawi(N),Latour(S),C… Mol Cell Biol 1998-07-16

...Syk. Surprisingly, Syk-deficient macrophages were impaired in the ability to survive or proliferate on plastic petri dis...

Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient…

Murphy(M A),Schnall(R G),Venter(D J),Barnett… Mol Cell Biol 1998-08-21

...Syk/ZAP-70 family of protein kinases.

Outside-In signaling of soluble and solid-phase fibrinogen through integrin alp…

Tohyama(Y),Tohyama(K),Tsubokawa(M),Asahi(M),… Blood 1998-09-10

...Syk was tyrosine-phosphorylated but FAK was dephosphorylated, whereas solid-phase fibrinogen promptly caused tyrosine ph...

Syk- and Lyn-dependent phosphorylation of Syk on multiple tyrosines following B…

Keshvara(L M),Isaacson(C C),Yankee(T M),Sara… J Immunol 1998-12-07

...Syk protein tyrosine kinase is an essential component of the B cell Ag receptor signaling pathway. Syk is phosphorylated...

The Src-like tyrosine kinase Hck is activated by granulocyte colony-stimulating…

Ward(A C),Monkhouse(J L),Csar(X F),Touw(I P)… Biochem Biophys Res Commun 1998-11-23

...Syk have been implicated in this process. However, it is unknown if other kinases might be involved in the diverse respo...

CD72-mediated B cell activation involves recruitment of CD19 and activation of …

Venkataraman(C),Lu(P J),Buhl(A M),Chen(C S),… Eur J Immunol 1998-12-15

...syk tyrosine phosphorylation suggesting that even under these conditions, CD72 signaling was independent of syk activati...

Epstein-Barr virus LMP2A drives B cell development and survival in the absence …

Caldwell(R G),Wilson(J B),Anderson(S J),Long… Immunity 1998-10-28

...Syk and Lyn protein tyrosine kinases. To analyze the significance of LMP2A expression in vivo, transgenic mice with B ce...

Antigens varying in affinity for the B cell receptor induce differential B lymp…

Kouskoff(V),Famiglietti(S),Lacaud(G),Lang(P)… J Exp Med 1998-11-17

...syk or Igalpha, was highly affinity dependent, whereas the ability to stimulate Lyn phosphorylation was less so. These d...

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