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Grb10/GrbIR as an in vivo substrate of Tec tyrosine kinase.

Mano(H),Ohya(K),Miyazato(A),Yamashita(Y),Oga… Genes Cells 1998-11-17

...Syk, Jak2 or insulin receptor. We also reveal that expression of Grb10/GrbIR suppresses the cytokine-driven and Tec-driv...

An improved retroviral gene transfer technique demonstrates inhibition of CD4-C…

Sugawara(T),Di Bartolo(V),Miyazaki(T),Nakauc… J Immunol 1998-10-06

ZAP-70 is a Syk family tyrosine kinase that plays an essential role in initiating TCR signals. Deficiency in ZAP-70 caus...

Differential requirements for ZAP-70 in TCR signaling and T cell development.

Kadlecek(T A),van Oers(N S),Lefrancois(L),Ol… J Immunol 1998-11-18

...Syk/ZAP-70 family of protein tyrosine kinases is indispensable for normal lymphoid development. Syk is necessary for the...

Mutations in the activation loop tyrosines of protein tyrosine kinase Syk abrog…

Zhang(J),Kimura(T),Siraganian(R P) J Immunol 1998-11-04

...Syk regulation, the two tyrosine residues at 519 and 520 in the putative activation loop of rat Syk were mutated to phen...

IL-2-induced cellular events.

Gómez(J),González(A),Martínez-A(C),Rebollo(A) Crit Rev Immunol 1998-08-31

...Syk-myc (channel 2), and a pathway leading to actin organization/bcl-2 expression (channel 3). The detailed hierarchical...

Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene acti…

Deckert(M),Tartare-Deckert(S),Hernandez(J),R… Immunity 1998-12-31

...Syk kinases, Ras, and calcineurin. Thus, 3BP2 is an important adaptor that may couple activated Zap-70/Syk to a LAT-cont...

Protein tyrosine kinase Syk is involved in Thy-1 signaling in rat basophilic le…

Tolar(P),Dráberová(L),Dráber(P) Eur J Immunol 1998-02-20

...Syk is also rapidly tyrosine phosphorylated upon Thy-1 cross-linking. Increased Syk tyrosine phosphorylation is observed...

Cloning and sequencing of the Sphingomonas (Pseudomonas) paucimobilis gene esse…

Nishikawa(S),Sonoki(T),Kasahara(T),Obi(T),Ku… Appl Environ Microbiol 1998-03-26

Sphingomonas (Pseudomonas) paucimobilis SYK-6 is able to grow on 5,5'-dehydrodivanillic acid (DDVA), syringate, vanillat...

Constitutive activation of TCR signaling molecules in IL-2-independent Herpesvi…

Noraz(N),Saha(K),Ottones(F),Smith(S),Taylor(… J Immunol 1998-03-18

...Syk protein tyrosine kinase. While Syk is generally not expressed in activated T cells, its introduction has been shown ...

Crystal-induced neutrophil activation VI. Involvment of FcgammaRIIIB (CD16) and…

Barabé(F),Gilbert(C),Liao(N),Bourgoin(S G),N… FASEB J 1998-02-27

...syk, tyrosine phosphorylation of the proto-oncogene Cbl, mobilization of calcium, and stimulation of the activity of pho...

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