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Identification of the Fc epsilonRI-activated tyrosine kinases Lyn, Syk, and Zap…

Kepley(C L),Wilson(B S),Oliver(J M) J Allergy Clin Immunol 1998-09-25

...Syk, previously linked to Fc epsilonRI-coupled rodent mast cell activation, as well as Zap-70, previously implicated in ...

Complementary roles for receptor clustering and conformational change in the ad…

Hato(T),Pampori(N),Shattil(S J) J Cell Biol 1998-08-03

...Syk) and fibrinogen-dependent phosphorylation of pp125(FAK), even in non-adherent cells. Thus, receptor clustering and a...

Cloning of a Sphingomonas paucimobilis SYK-6 gene encoding a novel oxygenase th…

Peng(X),Egashira(T),Hanashiro(K),Masai(E),Ni… Appl Environ Microbiol 1998-08-11

Sphingomonas paucimobilis SYK-6 transforms 2,2'-dihydroxy-3,3'-dimethoxy-5,5'-dicarboxybiphenyl (DDVA), a lignin-related...

BLNK: a central linker protein in B cell activation.

Fu(C),Turck(C W),Kurosaki(T),Chan(A C) Immunity 1998-09-01

...Syk tyrosine kinase with PLCgamma, the Vav guanine nucleotide exchange factor, and the Grb2 and Nck adapter proteins. Ty...

Regulation of tyrosine phosphorylation in isolated T cell membrane by inhibitio…

Jin(Y J),Friedman(J),Burakoff(S J) J Immunol 1998-08-27

...Syk, Zap70, and CD35 zeta are rapidly dephosphorylated. Preliminary characterizations indicate that a PTP distinct from ...

syk protein tyrosine kinase regulates Fc receptor gamma-chain-mediated transpor…

Bonnerot(C),Briken(V),Brachet(V),Lankar(D),C… EMBO J 1998-10-07

...syk activation, as well as overexpression of a syk dominant negative mutant, inhibited signal transduction without affec...

The real LAT steps forward.

Cantrell(D) Trends Cell Biol 1998-08-24

...Syk tyrosine kinases are important, but 'missing', links in this process. There has finally been some progress in charac...

Impaired viability and profound block in thymocyte development in mice lacking …

Pivniouk(V),Tsitsikov(E),Swinton(P),Rathbun(… Cell 1998-09-01

...Syk. We generated a SLP-76 null mutation in mice by homologous recombination in embryonic stem cells to evaluate the rol...

Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathwa…

Fütterer(K),Wong(J),Grucza(R A),Chan(A C),Wa… J Mol Biol 1998-09-16

...Syk family of kinases, consisting of ZAP-70 and Syk, play essential roles in a variety of immune and non-immune cells. T...

Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation o…

Walk(S F),March(M E),Ravichandran(K S) Eur J Immunol 1998-09-03

...syk-family kinases (Syk and ZAP-70) were able to phosphorylate the Y239 and Y240 sites, and less efficiently the Y317 si...

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